Renal Thrombotic Microangiopathy in Patients With Systemic Lupus Erythematosus and the Antiphospholipid Syndrome
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Thrombotic Microangiopathies with Rheumatologic Involvement
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2017, Handbook of Systemic Autoimmune DiseasesCitation Excerpt :There is no consensus on the management of renal impairment in APS patients. Anecdotal improvement of patients treated with angiotensin-converting enzyme (ACE) inhibitors and aspirin, corticosteroids, plasmapheresis, a mixture of immunosuppressive agents, ACE inhibitors, calcium channel blockers, and anticoagulation drugs have been reported [59–61], but controlled studies are not yet available to confirm these results. A positive response to rituximab is consistently reported, and this drug may be promising in the treatment of APS nephropathy [62,63].
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