The basis of autoimmunity: Part I mechanisms of aberrant self-recognition
References (87)
Cell
(1994)Cell
(1994)Adv. Immunol.
(1989)- et al.
Curr. Opin. Immunol.
(1992) - et al.
Immunity
(1994) - et al.
Immunol. Today
(1991) - et al.
Immunol. Today
(1993) - et al.
Cell
(1994) - et al.
Cell
(1991) - et al.
Cell
(1993)
Cell
Immunity
Cell
Immunol. Today
Immunol. Today
Immunochemistry
Clin. Immunol. Immunopathol.
Immunol. Today
Immunity
Adv. Immunol.
Immunol. Today
Immunol. Today
Cell
Immunol. Today
Nature
Annu. Rev. Immunol.
J. Clin. Invest.
J. Exp. Med.
Arthritis Rheum.
Ann. New York Acad. Sci.
Science
Diabetes
J. Exp. Med.
Nature
Nature
J. Exp. Med.
J. Exp. Med.
Proc. Natl Acad. Sci. USA
J. Immunol.
Immunol. Rev.
Immunol. Rev.
Proc. Natl Acad. Sci. USA
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2012, Animal BehaviourCitation Excerpt :Among other immune challenges the number of studies are small and the results ambiguous (Table 5), although it can be noted that both studies measuring the bacteria-killing activity in the blood reported enhanced innate responses in the carotenoid-supplemented group. One drawback of the vertebrate immune system is the risk of autoimmune reactions, that is when the organism's own immune system mistakenly identifies self-antigens as foreign and elicits responses against the organism's own cells (Theofilopoulos 1995). The severe consequences of autoimmune reactions and diseases are well known in humans, mice, Mus musculus, and chickens, Gallus gallus domesticus (Goldsby et al. 2003; Erf 2008).
The author thanks M. Duchosal, S.R. Duncan, D.H. Kono, D. Lo, P. Peterson, R. Rubin, J. Sprent and W. Weigle for critically reviewing the manuscript. The work of the author is supported by US National Institutes of Health grants AR31203 and AR39555.
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Argyrios N. Theofilopoulos is at the Dept of Immunology. The Scripps Research Institute, 10666 North Torrey Pines Road/IMM3, La Jolla, CA 92037, USA.