Abstract
Antiphospholipid syndrome (APS) is a cause of infertility and fetal loss. Ovarian stimulation can induce previously unknown APS. Ovarian hyperstimulation syndrome (OHS) is uncommon but potentially life-threatening, as well as catastrophic APS. A woman that simultaneously developed a severe OHS and a catastrophic APS is described in this paper. Both entities produced thrombotic cardiac and brain thrombosis. A peculiar mechanism of cardiac ischemia is also described. In spite of the life-threatening risk of this situation, the indication for preventive anti-aggregation and/or anticoagulation is not clear.
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Giner, V., Oltra, M.R., Esteban, M.J. et al. Catastrophic antiphospholipid syndrome related to severe ovarian hyperstimulation. Clin Rheumatol 26, 991–993 (2007). https://doi.org/10.1007/s10067-006-0231-4
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DOI: https://doi.org/10.1007/s10067-006-0231-4