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Juvenile idiopathische Arthritis

Der leise Zerstörer kindlicher Kiefergelenke

Juvenile idiopathic arthritis

The silent killer of pediatric temporomandibular joints

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Zusammenfassung

Kinder und Jugendliche mit juveniler idiopathischer Arthritis (JIA) haben in bis zu 87% der Fälle einen Befall der Kiefergelenke. Fast die Hälfte dieser Patienten weisen keine klinischen Symptome auf, sodass die Diagnosestellung mittels kontrastmittelverstärkter Magnetresonanztomographie erfolgt. Die Behandlung gründet sich auf medikamentöse, orthodontische und physiotherapeutische Maßnahmen, allerdings gibt es zur Wirkung der verschiedenen therapeutischen Ansätze kaum Daten. In den letzten Jahren wurde immer häufiger über die erfolgreiche Anwendung der bildgebend gesteuerten intraartikulären Steroidtherapie berichtet.

Abstract

Temporomandibular joint involvement occurs in up to 87% of the children with juvenile idiopathic with half of the patients being asymptomatic. In these cases the only option to diagnose arthritis of the temporomandibular joints is the gadolinium enhanced magnetic resonance imaging. Therapeutic approaches include drugs, orthodontic and physiotherapeutic management, although only scant data on the effectiveness of these treatments are available. Several reports in recent years have pointed to imaging guided intraarticular steroids as efficient treatment.

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Abbreviations

JIA:

Juvenile idiopathische Arthritis

TMJ:

„Temporomandibular joint(s)“, Kiefergelenk(e)

MRT:

Magnetresonanztomographie

CT:

Computertomographie

MIO:

Maximale Inzisoröffnung, der Abstand zwischen der okklusalen Flächen der Inzisoren

Literatur

  1. http://www.gkjr.de

  2. Tzaribachev N, Benseler SM, Tyrrell PN et al (2009) Predictors of delayed referral to a pediatric rheumatology center. Arthritis Rheum 61(10):1367–1372

    Article  CAS  PubMed  Google Scholar 

  3. Petty RE, Southwood TR, Manners P et al International League of Associations for Rheumatology (2004) International League of Associations for Rheumatology classification of juvenile idiopathic arthritis: 2nd revision, Edmonton, 2001. J Rheumatol 31(2):390–392

    PubMed  Google Scholar 

  4. Larheim TA, Haanaes HR (1981) Micrognathia, temporomandibular joint changes and dental occlusion in juvenile rheumatoid arthritis of adolescents and adults. Scand J Dent Res 89:329–338

    CAS  PubMed  Google Scholar 

  5. Larheim TA, Höyeraal HM, Stabrun AE, Haanaes HR (1982) The temporomandibular joint in juvenile rheumatoid arthritis. Radiographic changes related to clinical and laboratory parameters in 100 children. Scand J Rheumatol 11(1):5–12

    Article  CAS  PubMed  Google Scholar 

  6. Pedersen TK, Jensen JJ, Melsen B, Herlin T (2001) Resorption of the temporomandibular condylar bone according to subtypes of juvenile chronic arthritis. J Rheumatol 28:2109–2115

    CAS  PubMed  Google Scholar 

  7. Weiss PF, Arabshahi B, Johnson A et al (2008) High prevalence of temporomandibular joint arthritis at disease onset in children with juvenile idiopathic arthritis, as detected by magnetic resonance imaging but not by ultrasound. Arthritis Rheum 58(4):1189–1196

    Article  PubMed  Google Scholar 

  8. Müller L, Kellenberger CJ, Cannizzaro E et al (2009) Early diagnosis of temporomandibular joint involvement in juvenile idiopathic arthritis: a pilot study comparing clinical examination and ultrasound to magnetic resonance imaging. Rheumatology (Oxford) 48(6):680–685

    Google Scholar 

  9. Sommer OJ, Aigner F, Rudisch A et al (2003) Cross-sectional and functional imaging of the temporomandibular joint: radiology, pathology, and basic biomechanics of the jaw. Radiographics 23(6):e14

    Article  PubMed  Google Scholar 

  10. Arabshahi B, Cron RQ (2006) Temporomandibular joint arthritis in juvenile idiopathic arthritis: the forgotten joint. Curr Opin Rheumatol 18:490–495

    Article  PubMed  Google Scholar 

  11. Kjellberg H (1995) Juvenile chronic arthritis. Dentofacial morphology, growth, mandibular function and orthodontic treatment. Swed Dent J (Suppl) 109:1–156

    Google Scholar 

  12. Grosfeld O, Czarnecka B, Drecka-Kuzan K et al (1973) Clinical investigations of the temporomandibular joint in children and adolescents with rheumatoid arthritis. Scand J Rheumatol 2:145–149

    Article  CAS  PubMed  Google Scholar 

  13. Twilt M, Schulten AJ, Nicolaas P et al (2006) Facioskeletal changes in children with juvenile idiopathic arthritis. Ann Rheum Dis 65:823–825

    Article  CAS  PubMed  Google Scholar 

  14. Engstrom AL, Wanman A, Johansson A et al (2007) Juvenile arthritis and development of symptoms of temporomandibular disorders: a 15-year prospective cohort study. J Orofac Pain 21:120–126

    PubMed  Google Scholar 

  15. Bakke M, Zak M, Jensen BL et al (2001) Orofacial pain, jaw function, and temporomandibular disorders in women with a history of juvenile chronic arthritis or persistent juvenile chronic arthritis. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 92:406–414

    Article  CAS  PubMed  Google Scholar 

  16. Sheppard IM, Sheppard SM (1965) Maximal incisal opening: a diagnostic index? J Dent Med 20:13–15

    CAS  PubMed  Google Scholar 

  17. Küseler A, Pedersen TK, Herlin T, Gelineck J (1998) Contrast enhanced magnetic resonance imaging as a method to diagnose early inflammatory changes in the temporomandibular joint in children with juvenile chronic arthritis. J Rheumatol 25(7):1406–1412

    PubMed  Google Scholar 

  18. Küseler A, Pedersen TK, Gelineck J, Herlin T (2005) A 2 year follow-up study of enhanced magnetic resonance imaging and clinical examination of the temporomandibular joint in children with juvenile idiopathic arthritis. J Rheumatol 32(1):162–169

    PubMed  Google Scholar 

  19. Arabshahi B, Dewitt EM, Cahill AM et al (2005) Utility of corticosteroid injection for temporomandibular arthritis in children with juvenile idiopathic arthritis. Arthritis Rheum 52(11):3563–3569

    Article  CAS  PubMed  Google Scholar 

  20. Tzaribachev N, Fritz J, Horger M (2009) Spectrum of magnetic resonance imaging appearances of juvenile temporomandibular joints (TMJ) in non-rheumatic children. Acta Radiol 50(10):1182–1186

    Article  CAS  PubMed  Google Scholar 

  21. Twilt M, Schulten AJ, Verschure F et al (2008) Long-term follow-up of temporomandibular joint involvement in juvenile idiopathic arthritis. Arthritis Rheum 59(4):546–552

    Article  PubMed  Google Scholar 

  22. Pedersen TK, Küseler A, Gelineck J, Herlin T (2008) A prospective study of magnetic resonance and radiographic imaging in relation to symptoms and clinical findings of the temporomandibular joint in children with juvenile idiopathic arthritis. J Rheumatol 35(8):1668–1675

    PubMed  Google Scholar 

  23. Ringold S, Torgerson TR, Egbert MA, Wallace CA (2008) Intraarticular corticosteroid injections of the temporomandibular joint in juvenile idiopathic arthritis. J Rheumatol 35(6):1157–1164

    PubMed  Google Scholar 

  24. Ince DO, Ince A, Moore TL (2000) Effect of methotrexate on the temporomandibular joint and facial morphology in juvenile rheumatoid arthritis patients. Am J Orthod Dentofacial Orthop 118:75–83

    Article  CAS  PubMed  Google Scholar 

  25. Cahill AM, Baskin KM, Kaye RD et al (2007) CT-guided percutaneous steroid injection for management of inflammatory arthropathy of the temporomandibular joint in children. AJR Am J Roentgenol 188:182–186

    Article  PubMed  Google Scholar 

  26. Tzaribachev N, Fritz J, Holzer U et al (2007) JIA – the silent „killer“ of the temporomandibular joints. Arthritis Rheum 56(9):375

    Google Scholar 

  27. Fritz J, Thomas C, Tzaribachev N et al (2009) MRI-guided injection procedures of the temporomandibular joints in children and adults: technique, accuracy, and safety. AJR Am J Roentgenol 193(4):1148–1154

    Article  PubMed  Google Scholar 

  28. Tzaribachev N, Fritz J, Thomas C et al (2009) Long-term safety of intra-articular steroid injections for pediatric temporomandibular joint arthritis. EULAR SAT0511

  29. Saurenmann RK, Muller L, Schroeder S et al (2009) Efficacy of intra-articular steroid injection into the temporomandibular joint in children with juvenile idiopathic arthritis. ACR SUN243

  30. Stoustrup P, Kristensen KD, Küseler A et al (2008) Reduced mandibular growth in experimental arthritis in the temporomandibular joint treated with intra-articular corticosteroid. Eur J Orthod 30(2):111–119

    Article  PubMed  Google Scholar 

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Interessenkonflikt

Der korrespondierende Autor weist auf folgende Beziehung hin: Die Erforschung der Kiefergelenkarthritis wird finanziert im Rahmen eines „Investor originated Proposal“ durch Wyeth Pharma.

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Tzaribachev, N., Weber, D. & Horger, M. Juvenile idiopathische Arthritis. Z. Rheumatol. 69, 124–129 (2010). https://doi.org/10.1007/s00393-009-0562-z

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