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Cryptogenic organizing pneumonia (COP), as presentation of rheumatoid arthritis

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Abstract

We report a 65-year-old caucasian male, who presented criptogenic organizing pneumonia (COP) as first manifestation of rheumatoid arthritis. The patient started with fever, myalgias and progressive dyspnea in October 2004. The chest X-ray (CXR) and high resolution computed tomographic scan (HRCT) showed diffuse alveolar exudates with air bronchogram in both the lungs. An open lung biopsy was done and the histological image was compatible with COP. Six months later, a diagnosis of RA was made. Treatment with oral methotrexate and etanercept was prescribed with improvement in symptoms, physical examination, and laboratory tests. Even though COP after the joint involvement is found more frequently in RA, in rare cases it could be the first manifestation of this illness.

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References

  1. Matteson EL, Cohen MD, Conn DL (1998) Rheumatoid arthritis: clinical features and systemic involvement. In: Klippel JH, Dieppe PA (eds) Rheumatology, vol 1, 2nd edn. London, UK, 5:4.1–4.8

  2. Anaya JM, Diethelm L, Ortiz LA et al (1995) Pulmonary involvement in rheumatoid arthritis. Semin Arthritis Rheum 24:242–254

    Article  PubMed  CAS  Google Scholar 

  3. White ES, Tazelaar HD, Lynch JPIII (2003) Bronchiolar complications of connective tissue diseases. Semin Respir Crit Care Med 24:543–566

    Article  PubMed  Google Scholar 

  4. Ulubas B, Sahin G, Ozer C et al (2004) Bronchiolitis obliterans organizing pneumonia associated with sulfasalazine in a patient with rheumatoid arthritis. Clin Rheumatol 23:249–251

    Article  PubMed  Google Scholar 

  5. Epler G (2001) Bronchiolitis obliterans organizing pneumonia. Arch Intern Med 161:158–164

    Article  PubMed  CAS  Google Scholar 

  6. Cordier JF (2002) Update on cryptogenic organising pneumonia (idiopathic bronchiolitis obliterans organizing pneumonia). Swiss Med Wkly 132:588–591

    PubMed  Google Scholar 

  7. Rees JH, Woodhead MA, Sheppard MN, du Bois RM (1991) Rheumatoid arthritis and cryptogenic organizing pneumonia. Respir Med 85:243–246

    Article  PubMed  CAS  Google Scholar 

  8. Ippolito JA, Palmer L, Spector S, Kane PB, Gorevic PD (1993) Bronchiolitis obliterans organizing pneumonia and rheumatoid arthritis. Semin Arthritis Rheum 23:70–78

    Article  PubMed  CAS  Google Scholar 

  9. Kato T, Ubara Y, Sawa N et al (2004) An abrupt onset of seropositive polyarthritis with prominent distal tenosynovitis concomitant with bronchiolitis obliterans organizing pneumonia (BOOP): consideration of the relationship with RS3PE syndrome. Intern Med 43:143–147

    Article  PubMed  Google Scholar 

  10. Cordier JF (2000) Organizing pneumonia. Thorax 55:318–328

    Article  PubMed  CAS  Google Scholar 

  11. Kaushic P, Cooper ES, Banda VR et al (2005) Bronchiolitis obliterans with organizing pneumonia in rheumatoid arthritis: a fatal case and short review of literature. Rheumatol Int 25:391–393

    Article  Google Scholar 

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Authors and Affiliations

  1. Organización Médica de Investigación (OMI), Uruguay 725 PB. Código postal (1015 ABO), Buenos Aires, Argentina

    Javier Alberto Cavallasca, Mariana Caubet, Claudia Andrea Helling & Guillermo Alberto Tate

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  1. Javier Alberto Cavallasca
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  2. Mariana Caubet
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  3. Claudia Andrea Helling
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  4. Guillermo Alberto Tate
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Correspondence to Javier Alberto Cavallasca.

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Cavallasca, J.A., Caubet, M., Helling, C.A. et al. Cryptogenic organizing pneumonia (COP), as presentation of rheumatoid arthritis. Rheumatol Int 29, 99–101 (2008). https://doi.org/10.1007/s00296-008-0618-4

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  • DOI: https://doi.org/10.1007/s00296-008-0618-4

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