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Semi-automated digital image analysis of joint space width in knee radiographs

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Abstract

Objective

To design a semi-automated program to measure the minimum tibiofemoral joint space width (JSW) of knee radiographs.

Design

Bilateral knee radiographs were obtained twice within a 2 week period from 34 asymptomatic research participants. Radiographic images were analyzed to report both the variability of the image analysis program and the reproducibility of JSW measurements within a 2 week period. In addition, the results were compared with minimum JSW measurements read manually by an experienced musculoskeletal radiologist.

Results

The variability of the image analysis program was shown to be within one pixel. The results showed that reproducibility was better with the automated method. In addition, the manual method measured a greater minimum JSW than the automated method. There was no significant difference in between-day measurements. There was a significant difference reported between the automated and manual minimum JSW measurements.

Conclusion

A novel semi-automated method for measurement of JSW has been developed.

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References

  1. Osteoarthritis, vol 2003. Arthritis Foundation

  2. Gunther KP, Sun T. Reliability of radiographic assessment in hip and knee osteoarthritis. Osteoarthritis Cartilage 1999; 7:239―246.

    Article  CAS  PubMed  Google Scholar 

  3. Bruyere O, Henrotin YE, Honore A, Rovati LC, Seidel L, Dardenne C, Reginster JY. Impact of the joint space width measurement method on the design of knee osteoarthritis studies. Aging Clin Exp Res 2003; 15:136―141.

    PubMed  Google Scholar 

  4. Conrozier T, Lequesne M, Farvet H, Taccoen A, Mazieres B, Dougados M, Vignon M, Vignon E. Measurement of the radiological hip joint space width. An evaluation of various methods of measurement. J Osteoarthritis Res Soc Int 2001; 9:281―286.

    CAS  Google Scholar 

  5. Duryea J, Li J, Peterfy CG, Gordon C, Genant HK. Trainable rule-based algorithm for the measurement of joint space width in digital radiographic images of the knee. Med Phys 2000; 27:580―591.

    Article  CAS  PubMed  Google Scholar 

  6. Gordon CL, Wu C, Peterfy CG, Li J, Duryea J, Klifa C, Genant HK. Automated measurement of radiographic hip joint-space width. Med Phys 2001; 28:267―277.

    Article  CAS  PubMed  Google Scholar 

  7. Dacre JE, Huskisson E. The automatic assessment of knee radiographs in osteoarthritis using digital image analysis. Br J Rheumatol 1989; 28:506-―510.

    CAS  PubMed  Google Scholar 

  8. Duryea J, Zaim S, Genant HK. New radiographic-based surrogate outcome measures for osteoarthritis of the knee. Osteoarthritis Cartilage 2003; 11:102―110.

    Article  CAS  PubMed  Google Scholar 

  9. Buckland-Wright JC, Bird CF, Ritter-Hrncirik CA, Cline GA, Tonkin C, Hanartner TN, Ward RJ, Meyer JM, Meredith MP. X-ray technologists’ reproducibility from automated measurements of the medial tibiofemoral joint space width in knee osteoarthritis for a multicenter, multinational clinical trial. J Rheumatol 2003; 30:329―338.

    PubMed  Google Scholar 

  10. Roberts L. Machine perception of 3D solids: optical and electro-optical information processing. MIT Press, 1965.

  11. Canny J. A computational approach to edge detection. IEEE Trans Pattern Anal Machine Intell 1986; 6:679―698.

    Google Scholar 

  12. Duryea J, Zaim S, Genant HK. New radiographic-based surrogate outcome measures for osteoarthritis of the knee. Osteoarthritis Cartilage 2003; 11:102―110.

    Article  CAS  PubMed  Google Scholar 

  13. Steel RGD, Torrie JH. Principles and procedures of statistics: a biometrical approach. New York: McGraw-Hill, 1980:27.

  14. Bland JM, Altman DG. Statistical methods for assessing agreement between two methods of clinical measurement. Lancet 1986; I:307―310.

    Google Scholar 

  15. Peterfy C, Li J, Zaim S, Duryea J, Lynch J, Miaux Y, Yu W, Genant HK. Comparison of fixed-flexion positioning with fluoroscopic semi-flexed positioning for quantifying radiographic joint-space width in the knee: test-retest reproducibility. Skeletal Radiol 2003; 32:128―132.

    CAS  PubMed  Google Scholar 

  16. Mazzuca SA, Brandt KD, Buckland-Wright JC, Buckwalter KA, Katz BP, Lynch JA, Ward RJ, Emsley CL. Field test of the reproducibility of automated measurements of medial tibiofemoral joint space width derived from standardized knee radiographs. J Rheumatol 1999; 26:1359―1365.

    CAS  PubMed  Google Scholar 

  17. Mazzuca SA, Brandt KD, Buckwalter KA. Detection of radiographic joint space narrowing in subjects with knee osteoarthritis. Arthritis Rheum 2003; 48:385―390.

    Article  PubMed  Google Scholar 

  18. Piperno M, Le Graverand M-PH, Conrozier T, Bochu M, Mathieu P, Vignon E. Quantitative evaluation of joint space width in femorotibial osteoarthritis: comparison of three radiographic views. Osteoarthritis Cartilage 1998; 6:252―259.

    Article  CAS  PubMed  Google Scholar 

  19. Buckland-Wright JC, MacFarlane DG, Williams SA, Ward RJ. Accuracy and precision of joint space width measurements in standard and macro radiographs of osteoarthritic knees. Ann Rheum Dis 1995; 54:872―880.

    CAS  PubMed  Google Scholar 

  20. Lynch JA, Buckland-Wright JC, Macfarlane DG. Precision of joint space width measurement in knee osteoarthritis from digital image analysis of high definition macroradiographs. Osteoarthritis Cartilage 1993; 1:209―218.

    CAS  PubMed  Google Scholar 

  21. Mazzuca SA, Brandt KD, Buckwalter KA, Lane KA, Katz BP. Field test of the reproducibility of the semiflexed metatarsophalangeal view in repeated radiographic examinations of subjects with osteoarthritis of the knee. Arthritis Rheum 2002; 46:109―113.

    Article  PubMed  Google Scholar 

  22. Mazzuca SA, Brandt KD, Dieppe PA, Doherty M, Katz BP, Lane KA. Effect of alignment of the medial tibial plateau and X-ray beam on apparent progression of osteoarthritis in the standing anteroposterior knee radiograph. Arthritis Rheum 2001; 44:1786―1794.

    Article  CAS  PubMed  Google Scholar 

  23. Mazzuca SA, Brandt KD, Buckwalter KA, Lequesne M. Pitfalls in the accurate measurement of joint space narrowing in semiflexed, anteroposterior radiographic imaging of the knee. Arthritis Rheum 2004; 50:2508―2515.

    Article  PubMed  Google Scholar 

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Acknowledgement

This study was supported by NIH grant AR048768.

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Correspondence to K. R. Kaufman.

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Schmidt, J.E., Amrami, K.K., Manduca, A. et al. Semi-automated digital image analysis of joint space width in knee radiographs. Skeletal Radiol 34, 639–643 (2005). https://doi.org/10.1007/s00256-005-0908-9

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  • DOI: https://doi.org/10.1007/s00256-005-0908-9

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