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Secular trends in hip fracture incidence and recurrence

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Abstract

Summary

The decline in hip fracture incidence is now accompanied by a further reduction in the likelihood of a recurrent hip fracture among survivors of the first fracture.

Introduction

Hip fracture incidence is declining in North America, but trends in hip fracture recurrence have not been described.

Methods

All hip fracture events among Olmsted County, Minnesota residents in 1980–2006 were identified. Secular trends were assessed using Poisson regression, and predictors of recurrence were evaluated with Andersen–Gill time-to-fracture regression models.

Results

Altogether, 2,752 hip fractures (median age, 83 years; 76% female) were observed, including 311 recurrences. Between 1980 and 2006, the incidence of a first-ever hip fracture declined by 1.37%/year for women (p < 0.001) and 0.06%/year for men (p = 0.917). Among 2,434 residents with a first-ever hip fracture, the cumulative incidence of a second hip fracture after 10 years was 11% in women and 6% in men with death treated as a competing risk. Age and calendar year of fracture were independently associated with hip fracture recurrence. Accounting for the reduction in first-ever hip fracture rates over time, hip fracture recurrence appeared to decline after 1997.

Conclusion

A recent reduction in hip fracture recurrence is somewhat greater than expected from the declining incidence of hip fractures generally. Additional research is needed to determine the extent to which this can be attributed to improved patient management.

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References

  1. Klotzbuecher CM, Ross PD, Landsman PB et al (2000) Patients with prior fractures have an increased risk of future fractures: a summary of the literature and statistical synthesis. J Bone Miner Res 15:721–739

    Article  PubMed  CAS  Google Scholar 

  2. Stewart IM (1957) Fracture of neck of femur; survival and contralateral fracture. Br Med J 2:922–924

    Article  PubMed  CAS  Google Scholar 

  3. Melton LJ III, Ilstrup DM, Beckenbaugh RD et al (1982) Hip fracture recurrence: a population-based study. Clin Orthop 167:131–138

    PubMed  Google Scholar 

  4. Chiu KY, Pun WK, Luk KD et al (1992) Sequential fractures of both hips in elderly patients—a prospective study. J Trauma 32:584–587

    Article  PubMed  CAS  Google Scholar 

  5. Schroder HM, Petersen KK, Erlandsen M (1993) Occurrence and incidence of the second hip fracture. Clin Orthop 289:166–169

    PubMed  Google Scholar 

  6. Dretakis KE, Dretakis EK, Papakitsou EF et al (1998) Possible predisposing factors for the second hip fracture. Calcif Tissue Int 62:366–369

    Article  PubMed  CAS  Google Scholar 

  7. Chapurlat RD, Bauer DC, Nevitt M et al (2003) Incidence and risk factors for a second hip fracture in elderly women. The Study of Osteoporotic Fractures. Osteoporos Int 14:130–136

    PubMed  CAS  Google Scholar 

  8. Johnell O, Kanis JA, Oden A et al (2004) Fracture risk following an osteoporotic fracture. Osteoporos Int 15:175–179

    Article  PubMed  CAS  Google Scholar 

  9. Yamanashi A, Yamazaki K, Kanamori M et al (2005) Assessment of risk factors for second hip fractures in Japanese elderly. Osteoporos Int 16:1239–1246

    Article  PubMed  Google Scholar 

  10. Nymark T, Lauritsen JM, Ovesen O et al (2006) Short time-frame from first to second hip fracture in the Funen County Hip Fracture Study. Osteoporos Int 17:1353–1357

    Article  PubMed  CAS  Google Scholar 

  11. van Helden S, Cals J, Kessels F et al (2006) Risk of new clinical fractures within 2 years following a fracture. Osteoporos Int 17:348–354

    Article  PubMed  Google Scholar 

  12. Berry SD, Samelson EJ, Hannan MT et al (2007) Second hip fracture in older men and women: the Framingham Study. Arch Intern Med 167:1971–1976

    Article  PubMed  Google Scholar 

  13. Lonnroos E, Kautiainen H, Karppi P et al (2007) Incidence of second hip fractures. A population-based study. Osteoporos Int 18:1279–1285

    Article  PubMed  CAS  Google Scholar 

  14. Morin S, Rahme E, Behlouli H et al (2007) Effectiveness of antiresorptive agents in the prevention of recurrent hip fractures. Osteoporos Int 18:1625–1632

    Article  PubMed  CAS  Google Scholar 

  15. Melton LJ III, Atkinson EJ, Madhok R (1996) Downturn in hip fracture incidence. Public Health Rep 111:146–150, (discussion 151)

    PubMed  Google Scholar 

  16. Zingmond DS, Melton LJ III, Silverman SL (2004) Increasing hip fracture incidence in California Hispanics, 1983 to 2000. Osteoporos Int 15:603–610

    Article  PubMed  Google Scholar 

  17. Hiebert R, Aharonoff GB, Capla EL et al (2005) Temporal and geographic variation in hip fracture rates for people aged 65 or older, New York State, 1985–1996. Am J Orthop 34:252–255

    PubMed  Google Scholar 

  18. Jaglal SB, Weller I, Mamdani M et al (2005) Population trends in BMD testing, treatment, and hip and wrist fracture rates: are the hip fracture projections wrong? J Bone Miner Res 20:898–905

    Article  PubMed  Google Scholar 

  19. Gehlbach SH, Avrunin JS, Puleo E (2007) Trends in hospital care for hip fractures. Osteoporos Int 18:585–591

    Article  PubMed  CAS  Google Scholar 

  20. Melton LJ III, Therneau TM, Larson DR (1998) Long-term trends in hip fracture prevalence: the influence of hip fracture incidence and survival. Osteoporos Int 8:68–74

    Article  PubMed  Google Scholar 

  21. Macaulay W, Pagnotto MR, Iorio R et al (2006) Displaced femoral neck fractures in the elderly: hemiarthroplasty versus total hip arthroplasty. J Am Acad Orthop Surg 14:287–293

    PubMed  Google Scholar 

  22. Madhok R, Melton LJ III, Atkinson EJ et al (1993) Urban vs rural increase in hip fracture incidence. Age and sex of 901 cases 1980–89 in Olmsted County, U.S.A. Acta Orthop Scand 64:543–548

    Article  PubMed  CAS  Google Scholar 

  23. Melton LJ III (1996) History of the Rochester Epidemiology Project. Mayo Clin Proc 71:266–274

    Article  PubMed  Google Scholar 

  24. Melton LJ III (1997) The threat to medical-records research. N Engl J Med 337:1466–1470

    Article  PubMed  Google Scholar 

  25. Commission on Professional and Hospital Activities (1978) International classification of diseases, 9th revision, clinical modification, volume 1, diseases tabular list. Commission on Professional and Hospital Activities, Ann Arbor, MI

    Google Scholar 

  26. Arneson TJ, Melton LJ III, Lewallen DG et al (1988) Epidemiology of diaphyseal and distal femoral fractures in Rochester, Minnesota, 1965–1984. Clin Orthop 234:188–194

    PubMed  Google Scholar 

  27. Bergstralh EJ, Offord KP, Chu CP et al (1992) Calculating incidence, prevalence and mortality rates for Olmsted County, Minnesota: an update. Technical Report No. 49, Division of Biostatistics, Mayo Clinic, Rochester, MN

  28. Berry G (1983) The analysis of mortality by the subject-years method. Biometrics 39:173–184

    Article  PubMed  CAS  Google Scholar 

  29. Hastie TJ, Tibshirani RJ (1990) Generalized additive models. Chapman and Hall, London

    Google Scholar 

  30. Kaplan EL, Meier P (1958) Non-parametic estimation from incomplete observations. J Am Stat Assoc 53:457–481

    Article  Google Scholar 

  31. Tosteson AN, Gottlieb DJ, Radley DC et al (2007) Excess mortality following hip fracture: the role of underlying health status. Osteoporos Int 18:1463–1472

    Article  PubMed  CAS  Google Scholar 

  32. Gooley TA, Leisenring W, Crowley J et al (1999) Estimation of failure probabilities in the presence of competing risks: new representations of old estimators. Stat Med 18:695–706

    Article  PubMed  CAS  Google Scholar 

  33. Kalbfleisch JD, Prentice RL (1980) The statistical analysis of failure time data. Wiley, New York, NY

    Google Scholar 

  34. Therneau TM, Grambsch PM (2000) Modeling survival data: extending the Cox model. Springer, New York, NY

    Google Scholar 

  35. Cummings SR, Melton LJ (2002) Epidemiology and outcomes of osteoporotic fractures. Lancet 359:1761–1767

    Article  PubMed  Google Scholar 

  36. Fries J (1990) The compression of morbidity: progress and potential. J Insur Med 22:93–97

    Google Scholar 

  37. Giversen IM (2007) Time trends of mortality after first hip fractures. Osteoporos Int 18:721–732

    Article  PubMed  CAS  Google Scholar 

  38. Mackey DC, Lui LY, Cawthon PM et al (2007) High-trauma fractures and low bone mineral density in older women and men. JAMA 298:2381–2388

    Article  PubMed  CAS  Google Scholar 

  39. Elliot-Gibson V, Bogoch ER, Jamal SA et al (2004) Practice patterns in the diagnosis and treatment of osteoporosis after a fragility fracture: a systematic review. Osteoporos Int 15:767–778

    Article  PubMed  CAS  Google Scholar 

  40. Burge R, Dawson-Hughes B, Solomon DH et al (2007) Incidence and economic burden of osteoporosis-related fractures in the United States, 2005–2025. J Bone Miner Res 22:465–475

    Article  PubMed  Google Scholar 

  41. Kannus P, Niemi S, Parkkari J et al (2006) Nationwide decline in incidence of hip fracture. J Bone Miner Res 21:1836–1838

    Article  PubMed  Google Scholar 

  42. Stenvall M, Olofsson B, Lundstrom M et al (2007) A multidisciplinary, multifactorial intervention program reduces postoperative falls and injuries after femoral neck fracture. Osteoporos Int 18:167–175

    Article  PubMed  CAS  Google Scholar 

  43. Cree MW, Juby AG, Carriere KC (2003) Mortality and morbidity associated with osteoporosis drug treatment following hip fracture. Osteoporos Int 14:722–727

    Article  PubMed  Google Scholar 

  44. Berggren M, Stenvall M, Olofsson B et al (2008) Evaluation of a fall-prevention program in older people after femoral neck fracture: a one-year follow-up. Osteoporos Int 19:801–809

    Article  PubMed  CAS  Google Scholar 

  45. Lyles KW, Colon-Emeric CS, Magaziner JS et al (2007) Zoledronic acid and clinical fractures and mortality after hip fracture. N Engl J Med 357:1799–1809

    Article  PubMed  CAS  Google Scholar 

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Acknowledgements

The authors would like to thank Leona Bellrichard, R.N.; Marcia Erickson, R.N.; Wendy Gay, R.N.; Joan LaPlante, R.N.; and Barbara Nolte, R.N. for their assistance with data collection and Mary Roberts for the help in preparing the manuscript. This project was supported in part by grants AG-04875 and AR-30582 from the National Institutes of Health, U.S. Public Health Service.

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Correspondence to L. J. Melton III.

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Melton, L.J., Kearns, A.E., Atkinson, E.J. et al. Secular trends in hip fracture incidence and recurrence. Osteoporos Int 20, 687–694 (2009). https://doi.org/10.1007/s00198-008-0742-8

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  • DOI: https://doi.org/10.1007/s00198-008-0742-8

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