Summary
CRP levels in 194 serum samples from 43 SLE patients were measured. Patients with inactive disease have levels below 10 μg/ml; patients with active SLE have higher levels, but never over 50 μg/ml. In the presence of infection or inflammatory processes, regardless of the activity of SLE, the levels are significantly higher (p<0.05), and well over 50 μg/ml. Both active SLE patients and inactive SLE patients with local infections have levels between 10 μg/ml and 50 μg/ml. In this situation, the presence of anti-DNA antibodies strongly suggests disease activity (82% versus 9%, p<0.05). The clinical and physiopathological meaning of these findings is discussed.
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Linares, L.F., Gomez-Reino, J.J., Carreira, P.E. et al. C-reactive protein (CRP) levels in systemic lupus erythematosus (SLE). Clin Rheumatol 5, 66–69 (1986). https://doi.org/10.1007/BF02030970
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DOI: https://doi.org/10.1007/BF02030970