Abstract
In an 11-year-old boy severe dermatomyositis occurred a few days after injection in the jaw of a local anaesthetic of the amide type for tooth extraction. The patient's grandmother was affected by progressive scleroderma at the age of 34 years, also after injection of a local anaesthetic for dental treatment. Both cases are discussed with special reference to the immuno-genetic aspects of the origin of dermatomyositis.
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Abbreviations
- ADMS:
-
adult dermatomyositis
- C2:
-
complement 2
- C3:
-
complement 3
- C4:
-
complement 4
- ESR:
-
erythrocyte sedimentation rate
- HLA:
-
histocompabibility locus antigen
- IgE:
-
immunoglobulin E
- JDMS:
-
juvenile dermatomyositis
References
Bohan A, Peter JB (1975) Polymyositis and dermatomyositis (first of two parts). N Engl J Med 292:344–347
Bohan A, Peter JB (1975) Polymyositis and dermatomyositis (second of two parts). N Engl J Med 292:403–407
Cook CD, Rosen IS, Banker BQ (1963) Dermatomyositis and focal scleroderma. Pediatr Clin N Am 10:979–1016
Currie S, Saunders M, Knowls M, Brown AE (1971) Immunological aspects of polymyositis. Q J Med 40:63–84
Dawkins RL, Mastaglia FL (1973) Cell-mediated cytotoxicity to muscle in polymyositis: effects of immunosuppression. N Engl J Med 228:434–438
Dubowitz V, Brooke MH (1973) Muscle biopsy — a modern approach. Saunders, London
Lambie JA, Duff IF (1963) Familial occurrence of dermatomyositis, case reports and a family survey. Ann Intern Med 59:839–847
Leddy GP, Griggs RC, Klemperer MR, Frank MM (1975) Hereditary complement (C2) deficiency with dermatomyositis. Am J Med 58:83–91
Lewkonia RM, Buxton PH (1973) Myositis in father and daughter. J Neurol Neurosurg Psychiatry 36:820–825
Malleson P (1982) Juvenile dermatomyositis, a review. J R Soc Med 75:33–37
Miller G, Heckmatt JZ, Dubowitz V (1983) Drug treatment of juvenile dermatomyositis. Arch Dis Child 58:445–450
Pachmann LM, Cooke N (1980) Juvenile dermatomyositis: a clinical and immunological study. J Pediatr 96:226–234
Vialkowitsch I, Schlote W (1984) The bitten fiber — a muscle fiber deformation suggestive of autoimmune etiology. (In preparation)
Whitaker JN, Engel WK (1972) Vascular deposits of immunoglobulins and complement in idiopathic inflammatory myopathy. N Engl J Med 286:333–338
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Rose, T., Nothjunge, J. & Schlote, W. Familial occurrence of dermatomyositis and progressive scleroderma after injection of a local anaesthetic for dental treatment. Eur J Pediatr 143, 225–228 (1985). https://doi.org/10.1007/BF00442147
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DOI: https://doi.org/10.1007/BF00442147