Regular ArticleCloning, Characterization, and the Complete 56.8-Kilobase DNA Sequence of the Human NOTCH4 Gene☆,☆☆
References (75)
- et al.
Choosing cell fate: A view from the Notch locus
Trends Genet.
(1991) - et al.
DNA sequence analysis of 66 kb of the human MHC class II region encoding a cluster of genes for antigen processing
J. Mol. Biol.
(1992) - et al.
Transcription termination and 3′ processing: the end is in site
Cell
(1985) - et al.
NF-κB and related proteins: Rel/Dorsal homologies meet ankyrin-like repeats
Trends Biochem. Sci.
(1992) - et al.
Intracellular cleavage of Notch leads to a heterodimeric receptor on the plasma membrane
Cell
(1997) - et al.
Map of the human MHC
Immunol. Today
(1993) - et al.
Expression of an extracellular deletion of Xotch diverts cell fate in Xenopus embryos
Cell
(1993) - et al.
TAN-1, the human homolog of Drosophila Notch gene, is broken by chromosomal translocations in T lymphoblastic neoplasms
Cell
(1991) - et al.
Notch: Neurogenesis is only part of the picture
Cell
(1993) - et al.
The choice of cell fate in the epidermis of Drosophila
Cell
(1991)
Jagged: A mammalian ligand that activates Notch1
Cell
(1995)
Human homolog of rat Jagged1 expressed by marrow stroma inhibits differentiation of 32D cells through interaction with Notch1
Immunity
(1998)
Single amino acid substitutions in EGF-like elements of Notch and Delta modify Drosophila development and affect cell adhesion in vitro
Neuron
(1992)
GATA-binding transcription factors in hematopoietic cells
Blood
(1992)
Kuzbanian controls proteolytic processing of Notch and mediates lateral inhibition during Drosophila and vertebrate neurogenesis
Cell
(1997)
Expression analysis of a Notch homologue in the mouse embryo
Dev. Biol.
(1992)
Specific truncations of Drosophila Notch define dominant activated and dominant negative forms of the receptor
Cell
(1993)
Role of neurogenic genes in establishment of follicle cell fate and oocyte polarity during oogenesis in Drosophila
Cell
(1991)
The “initiator” as a transcription control element
Cell
(1989)
Intrinsic activity of the Lin-12 and Notch intracellular domains in vivo
Cell
(1993)
Three genes in the human MHC class III region near the junction with the class. II. Gene for receptor of advanced glycosylation end products, homeobox gene and a Notch homolog, human counterpart of mouse mammary tumor gene int-3
Genomics
(1994)
Gene organization of human Notch4 and (CTG)n
Gene
(1997)
Physical interaction between a novel domain of the receptor Notch and the transcription factor RBP-Jκ Su(H)
Curr. Biol.
(1995)
Opa: A novel family of transcribed repeats shared by the Notch locus and other developmentally regulated loci in D. melanogaster
Cell
(1985)
Reciprocal changes in expression of the receptor Lin-12 and its ligand Lag-2 prior to commitment in a C. elegans cell fate decision
Cell
(1994)
glp-1 and lin-12, genes implicated in distal cell- cell interactions in C. elegans, encode similar transmembrane proteins
Cell
(1989)
Notch signaling
Science
(1995)
Trinucleotide repeat expansions and human genetic disease
BioEssays
(1994)
Molecular basis of myotonic dystrophy: Expansion of a trinucleotide (CTG) repeat at the 3′end of a transcript encoding a protein kinase family member
Cell
(1992)
Notch is required for successive cell decisions in the developingDrosophila
Genes Dev.
(1989)
Lag-1, a gene required for Lin-12 and Glp-1 signaling in C. elegans, is homologous to human CBF1 and Drosophila Su(H)
Development
(1996)
Xotch, theXenopusDrosophila
Science
(1990)
Feed-back mechanism affecting Notch activation at the dorsoventral boundary in the Drosophila wing
Development
(1997)
An erythrocyte-specific DNA binding factor recognizes a regulatory sequence common to all chicken globin genes
Proc. Natl. Acad. Sci. USA
(1988)
Complex spatial and temporal regulation of Notch expression during embryonic and imaginal development ofDrosophila:
J. Cell. Biol.
(1991)
An activated Notch receptor blocks cell-fate commitment in the developingDrosophila
Nature
(1993)
Expression pattern of Motch, a mouse homolog ofDrosophila
Development
(1992)
Cited by (0)
- ☆
Sequence data described in this paper have been deposited with the EMBL/GenBank Data Libraries under Accession No. U89335 for the genomic sequence and Accession No. U95299 for the cDNA sequence of human NOTCH4.
- ☆☆
M. D. AdamsC. FieldsJ. C. Venter
- 1
L. Li and G. M. Huang made equal contributions to this work.
- 2
Present address: Pangea Systems Inc., 1999 Harrison Street, Suite 1100, Oakland, CA 94612.
- 3
To whom correspondence should be addressed at Department of Molecular Biotechnology, University of Washington, Box 357730, Seattle, WA 98195. Telephone: (206) 616-5104. Fax: (206) 685-7301.
Copyright © 1998 Academic Press. All rights reserved.