Table 2.

Cartilage thickness and percent of denuded bone for all participants.

Outcome, n = 578	Baseline (95% CI)	Yr 1 (95% CI)	Mean Change Over 1 Yr (95% CI)
Medial tibia
Cartilage thickness, mm
Overall	1.63 (1.60 to 1.65)	1.61 (1.59 to 1.63)	−0.01 (−0.02 to −0.01)^*
Center	2.08 (2.01 to 2.12)	2.05 (2.01 to 2.08)	−0.03 (−0.04 to −0.02)^*
Anterior	1.45 (1.43 to 1.48)	1.45 (1.42 to 1.47)	−0.00 (−0.01 to 0.00)
Posterior	1.40 (1.38 to 1.42)	1.40 (1.38 to 1.42)	−0.00 (−0.01 to 0.00)
Denuded bone, %
Overall	1.41 (1.08 to 1.73)	1.86 (1.47 to 2.24)	0.45 (0.29 to 0.62)^*
Center	0.52 (0.28 to 0.76)	0.92 (0.54 to 1.30)	0.40 (0.19 to 0.61)^*
Anterior	0.87 (0.40 to 1.34)	1.06 (0.60 to 1.53)	0.19 (0.04 to 0.35)^*
Posterior	0.81 (0.47 to 1.15)	0.85 (0.53 to 1.18)	0.04 (−0.05 to 0.13)
Lateral tibia
Cartilage thickness, mm
Overall	1.96 (1.93 to 1.99)	1.95 (1.92 to 1.98)	−0.01 (−0.02 to −0.01)^*
Center	2.97 (2.91 to 3.03)	2.96 (2.90 to 3.02)	−0.01 (−0.03 to 0.00)^*
Anterior	1.64 (1.61 to 1.67)	1.64 (1.62 to 1.67)	0.00 (−0.00 to 0.01)
Posterior	1.64 (1.61 to 1.67)	1.63 (1.60 to 1.66)	−0.01 (−0.02 to −0.01)^*
Denuded bone, %
Overall	1.00 (0.74 to 1.26)	1.07 (0.79 to 1.34)	0.07 (0.01 to 0.12)^*
Center	0.17 (0.05 to 0.29)	0.23 (0.05 to 0.42)	0.07 (−0.01 to 0.14)
Anterior	0.95 (0.44 to 1.46)	0.94 (0.43 to 1.46)	0.01 (−0.11 to 0.09)
Posterior	2.97 (2.24 to 3.70)	3.16 (2.39 to 3.92)	0.19 (0.06 to 0.32)^*