Late-onset PsA | Late-onset PsO |
---|---|
More common in females | Less frequent family history of PsO |
Less common presence of HLA-C*06 | Less common presence of HLA-Cw6 |
Longer PsO duration | More common presence of comorbidities |
More aggressive disease | Less severe skin involvement |
↑ levels of inflammation markers | |
↑ mortality risk | |
↑ baseline mSS | |
↑ BMI | |
↓ dactylitis | |
↓ nail involvement | |
↓ PASI scores |
↵aCut-off for late-onset disease differs between studies. mSS: modified Steinbrocker score; PASI: Psoriasis Area Severity Index; PsA: psoriatic arthritis; PsO: psoriasis.