Table 3B.

Estimates of meaningful within-patient change by WOMAC domain and study as percentage change.

WOMAC DomainStudy
123
1-category Change in PGA-OA2-category Change in PGA-OA1-category Change in PGA-OA2-category Change in PGA-OA1-category Change in PGA-OA2-category Chan in PGA-OA
Pain15.51
(14.69–16.34)
31.02
(29.38–32.67)
13.51
(12.74–14.28)
27.02
(25.48–28.56)
15.93
(15.54–16.32)
31.85
(31.07–32.63)
Physical Function15.31
(14.51–16.10)
30.61
(29.02–32.21)
12.50
(11.81–13.20)
25.01
(23.61–26.41)
15.63
(15.26–16.01)
31.27
(30.52–32.01)
Stiffness15.36
(14.42–16.29)
30.72
(28.85–32.59)
13.24
(12.14–14.34)
26.47
(24.28–28.67)
16.23
(15.76–16.70)
32.46
(31.52–33.40)
Total15.15
(14.37–15.93)
30.30
(28.74–31.85)
12.90
(12.19–13.62)
25.80
(24.37–27.24)
15.51
(15.14–15.88)
31.02
(30.29–31.76)
  • 95% CIs are shown for each value. PGA-OA: patient global assessment of osteoarthritis; WOMAC: Western Ontario and McMaster Universities Osteoarthritis Index.