WOMAC Domain | Study 1 | Study 2 | Study 3 | |||
---|---|---|---|---|---|---|
Original Units | Percentage | Original Units | Percentage | Original Units | Percentage | |
Pain | 0.613 | 0.576 | 0.493 | 0.477 | 0.600 | 0.550 |
Physical Function | 0.624 | 0.589 | 0.500 | 0.491 | 0.610 | 0.560 |
Stiffness | 0.549 | 0.521 | 0.366 | 0.358 | 0.540 | 0.510 |
Total | 0.615 | 0.578 | 0.479 | 0.479 | 0.600 | 0.560 |
Correlations between change in WOMAC domains and change in PGA-OA at the primary time points of week 16 in studies 1 and 3 and week 24 in study 2. PGA-OA: patient global assessment of osteoarthritis; WOMAC: Western Ontario and McMaster Universities Osteoarthritis Index.