Table 3A.

Estimates of meaningful within-patient change by WOMAC domain and study in original units.

WOMAC DomainStudy
123
1-category Change in PGA-OA2-category Change in PGA-OA1-category Change in PGA-OA2-category Change in PGA-OA1-category Change in PGA-OA2-category Chan in PGA-OA
Pain1.142.280.911.821.152.30
(1.08–1.20)(2.16–2.40)(0.86–0.96)(1.72–1.92)(1.12–1.18)(2.25–2.35)
Physical Function1.142.280.851.701.132.26
(1.08–1.20)(2.16–2.40)(0.81–0.90)(1.61–1.80)(1.11–1.16)(2.21–2.32)
Stiffness1.162.310.841.681.142.27
(1.09–1.22)(2.17–2.45)(0.78–0.90)(1.56–1.81)(1.11–1.17)(2.21–2.33)
Total1.142.270.861.721.122.25
(1.08–1.19)(2.16–2.39)(0.81–0.91)(1.63–1.82)(1.10–1.15)(2.20–2.30)
  • 95% CIs are shown for each value. PGA-OA: patient global assessment of osteoarthritis; WOMAC: Western Ontario and McMaster Universities Osteoarthritis Index.