Table 2.

Risk factors for noncompression peripheral neuropathy in SSc.

StudyNeuropathy Risk FactorMethod of Assessment
Manneschi 200535Advanced dSScN/A
Del Rosso 200318Anticentromere antibodyIndirect immunofluorescence
Bandinelli 201010Ischemia of vasa nervorumUltrasound
Ostojic 201344Metoclopramide and iron deficiency anemiaN/A
Barbosa 2017114PembrolizumabN/A
Bignotti 201513Reduced nerve densityUltrasound
Agarwal 198761SilicosisN/A
Averbuch-Heller 1992120UremiaBlood level

  • dSSc: diffuse systemic sclerosis; N/A: not applicable; SSc: systemic sclerosis.