Patient demographics and defining clinical characteristics in men and women with axSpA at enrollmenta.
| Overall, N = 504b | Men, n = 307 | Women, n = 191 | Pc | |
|---|---|---|---|---|
| Diagnosis, n (%) | ||||
| AS | 414 (82.1) | 252 (82.1) | 156 (81.7) | 0.91 |
| nr-axSpA | 90 (17.9) | 55 (17.9) | 35 (18.3) | |
| Age, yrs, mean (SD) | 47.4 (13.7) | 47.3 (13.9) | 47.7 (13.5) | 0.75d |
| Race, n (%) | ||||
| White | 449 (91.8) | 276 (91.4) | 172 (92.5) | 0.08e |
| Black | 9 (1.8) | 3 (1.0) | 6 (3.2) | |
| Other | 31 (6.3) | 23 (7.6) | 8 (4.3) | |
| BMI, kg/m2, mean (SD) | 29.9 (7.1) | 29.8 (6.0) | 30.0 (8.5) | 0.32d |
| BMI category, kg/m2, n (%) | ||||
| Normal/underweight, < 25 | 124 (25.2) | 64 (21.5) | 60 (31.7) | 0.04f |
| Overweight, 25 to < 30 | 157 (31.9) | 102 (34.3) | 54 (28.6) | |
| Obese, ≥ 30 | 211 (42.9) | 131 (44.1) | 75 (39.7) | |
| Symptom duration, yrs, mean (SD) | 16.8 (12.1) | 17.6 (12.3) | 15.7 (11.6) | 0.09d |
| Disease duration, yrs, mean (SD) | 9.5 (10.5) | 10.3 (10.8) | 8.2 (9.9) | 0.02d |
| Time from symptom onset to diagnosis, yrs, mean (SD) | 7.3 (8.9) | 7.3 (8.9) | 7.6 (9.0) | 0.79d |
| HLA-B27 positive, n (%) | 354 (70.2) | 224 (73.0) | 124 (64.9) | 0.06f |
↵a All values were calculated based on available data, and all variables had < 20% missing data.
↵b Six patients did not have sex information available at enrollment or follow-up.
↵c P values compared men vs women with axSpA. P values calculated using
↵d Wilcoxon rank-sum test,
↵e Fisher exact test, and
↵f chi-square test.
AS: ankylosing spondylitis; axSpA: axial spondyloarthritis; nr-axSpA: nonradiographic axial spondyloarthritis.