n (%) | |
---|---|
Female sex | 165 (51) |
Ethnicity | |
European | 110 (34) |
Non-Europeana | 156 (48) |
Mixed European-non-European | 58 (18) |
NLE | 175 (54) |
Cardiac | 23 (13) |
1st degree CHB | 2 (9) |
2nd degree CHB | 2 (9) |
3rd degree CHB | 14 (61) |
Endocardial fibroelastosis | 7 (30) |
Myocarditis | 5 (22) |
Hepaticb | 92 (53) |
Hematologic | 69 (39) |
Neutropenia | 54 (78)c |
Thrombocytopenia | 11 (16)c |
Neutropenia and thrombocytopenia | 4 (6)c |
Cutaneous | 37 (21) |
Neurologic (benign macrocephaly) | 13 (7) |
Data presented as n (%). Median values for neutropenia 0.78 × 109/L (range 0.26–0.99), thrombocytopenia 98 × 109/L (range 63–186), ALT 71 U/L (range 52–314), AST 97 U/L (range 77–280).
↵a Non-European group comprised patients of East Asian (n = 49, 31%), South Asian (n = 42, 27%), African (n = 32, 21%), Latin American (n = 8, 5%), and mixed Non-European (n = 25, 16%) ethnicity.
↵b Age-adjusted normal values were used.
↵c Shown as percentage of patients with hematologic involvement and not of total cohort.
ALT: alanine aminotransferase, AST: aspartate aminotransferase; CHB: complete heart block; NLE: neonatal lupus erythematosus.