Incidence and HR for cancer and mortality in 1:2 matched cohorts aged 41–55 years.
| Non-gout | Gout | |
|---|---|---|
| Cancer incidence | ||
| Patients, n | 8352 | 4176 |
| PY | 84,645 | 42,202.5 |
| Events | 611 | 390 |
| Rate per 1000 PY | 7.218 | 9.241 |
| HR (95% CI)a | Ref | 1.224 (1.073–1.398)* |
| All-cause mortality | ||
| PY | 87,316.38 | 44,038.43 |
| Events | 172 | 132 |
| Rate per 1000 PY | 1.970 | 2.997 |
| HR (95% CI)a | Ref | 1.457 (1.149–1.847)* |
| Death from cancer | ||
| PY | 87,316.38 | 44,038.43 |
| Events | 68 | 49 |
| Rate per 1000 PY | 0.779 | 1.113 |
| HR (95% CI)b | Ref | 1.470 (1.020–2.136)* |
| Death from other causes | ||
| PY | 87,316.38 | 44,038.43 |
| Events | 104 | 83 |
| Rate per 1000 PY | 1.191 | 1.885 |
| HR (95% CI)b | Ref | 1.440 (1.074–1.931)* |
↵* Significant.
↵a HR from the stratified Cox proportional hazards regression model, adjusted for residence, income, smoking, drinking, comorbidities (DM, hypertension, kidney disease, COPD), BMI, SBP, DBP, glucose, total cholesterol, and hemoglobin.
↵b HR from subdistribution hazards model, adjusted for residence, income, smoking, drinking, comorbidities (DM, hypertension, kidney disease, COPD), BMI, SBP, DBP, glucose, total cholesterol, and hemoglobin. COPD: chronic obstructive pulmonary disease; DBP: diastolic blood pressure; DM: diabetes mellitus; PY: person-years; SBP: systolic blood pressure.