RA Cohort | Non-RA | |||||||
---|---|---|---|---|---|---|---|---|
Overall, n = 120 | 1980–89, n = 48 | 1990–99, n = 47 | 2000–09, n = 25 | Overall, N = 94 | 1980–89, n = 38 | 1990–99, n = 24 | 2000–09, n = 32 | |
Age, yrs, at MI/stroke | 75.2 (12.0) | 76.7 (10.1) | 75.0 (13.4) | 72.7 (12.6) | 75.4 (11.9) | 77.1 (10.8) | 73.7 (13.3) | 74.6 (12.3) |
Female sex | 71 (59) | 32 (67) | 26 (55) | 13 (52) | 62 (66) | 25 (66) | 15 (63) | 22 (69) |
Years from RA/index to MI /stroke | 11.1 (8.3) | 14.8 (9.8) | 10.1 (6.4) | 5.8 (3.8) | 10.6 (7.5) | 14.5 (8.9) | 10.3 (5.2) | 6.2 (3.9) |
RF/CCP-positive | 86 (72) | 32 (67) | 36 (77) | 18 (72) | – | – | – | – |
Ever smoker | 75 (63) | 33 (69) | 29 (62) | 13 (52) | 51 (54) | 20 (53) | 16 (67) | 15 (47) |
Years from MI/stroke to last follow-up, median (IQR) | 3.3 (0.6–7.2) | 2.0 (0.1–6.7) | 4.7 (2.3–8.8) | 3.5 (0.2–6.1) | 4.2 (0.5–8.2) | 3.4 (0.1–8.9) | 5.2 (1.3–8.1) | 4.1 (1.1–6.7) |
Values are mean (SD) for continuous characteristics unless otherwise specified, and N (%) for discrete characteristics. There were no significant differences in characteristics of the RA and non-RA cohorts overall or by decade of RA incidence/index. Significant differences between decades among the RA cohort and among the non-RA cohort included years from RA/index date to MI/stroke (both P < 0.001). CCP: cyclic citrullinated peptide; CVD: cardiovascular disease; MI: myocardial infarction; RA: rheumatoid arthritis; RF: rheumatoid factor.