Table 4.

Characteristics of patients with incident CVD events during the follow-up, by decade of RA incidence/index.

RA CohortNon-RA
Overall, n = 1201980–89, n = 481990–99, n = 472000–09, n = 25Overall, N = 941980–89, n = 381990–99, n = 242000–09, n = 32
Age, yrs, at MI/stroke75.2 (12.0)76.7 (10.1)75.0 (13.4)72.7 (12.6)75.4 (11.9)77.1 (10.8)73.7 (13.3)74.6 (12.3)
Female sex71 (59)32 (67)26 (55)13 (52)62 (66)25 (66)15 (63)22 (69)
Years from RA/index to MI /stroke11.1 (8.3)14.8 (9.8)10.1 (6.4)5.8 (3.8)10.6 (7.5)14.5 (8.9)10.3 (5.2)6.2 (3.9)
RF/CCP-positive86 (72)32 (67)36 (77)18 (72)
Ever smoker75 (63)33 (69)29 (62)13 (52)51 (54)20 (53)16 (67)15 (47)
Years from MI/stroke to last follow-up, median (IQR)3.3 (0.6–7.2)2.0 (0.1–6.7)4.7 (2.3–8.8)3.5 (0.2–6.1)4.2 (0.5–8.2)3.4 (0.1–8.9)5.2 (1.3–8.1)4.1 (1.1–6.7)
  • Values are mean (SD) for continuous characteristics unless otherwise specified, and N (%) for discrete characteristics. There were no significant differences in characteristics of the RA and non-RA cohorts overall or by decade of RA incidence/index. Significant differences between decades among the RA cohort and among the non-RA cohort included years from RA/index date to MI/stroke (both P < 0.001). CCP: cyclic citrullinated peptide; CVD: cardiovascular disease; MI: myocardial infarction; RA: rheumatoid arthritis; RF: rheumatoid factor.