Comparison of change from baseline in radiographic mSASSS at Week 104: AS-001 vs OASIS data (second reading of films).
| AS-001 Apremilast 30 mg Twice Daily Population, n = 98 | OASIS-Matched Population, n = 56 | OASIS Overall Population, n = 178 | |
|---|---|---|---|
| Baseline mSASSS, mean (SD) | 12.3 (17.9) | 7.4 (10.8) | 7.9 (12.6) |
| mSASSS to Week 104, mean change from baseline (SD) | 0.87 (2.5) | 0.55 (3.2) | 0.63 (2.5) |
| Patients without radiographic progressiona, % | 70.4 | 82.1 | 76.4 |
↵a Radiographic progression was defined as a change in mSASSS ≥ 1 for this analysis. mSASSS: modified Stoke Ankylosing Spondylitis Spine Score; OASIS: Outcome Assessments in Ankylosing Spondylitis International Study.