Effect of oral manifestation by frequency on SS-related quality of life (n = 2961).
| Monthly | Weekly Adjusted OR (95% CI) | Daily | |
|---|---|---|---|
| Dry mouth, n = 2875 | |||
| Challenge and burdena | 1.17 (0.52–2.65) | 1.27 (0.61–2.62) | 2.25 (1.15–4.44) |
| Functional interference | 1.65 (0.75–3.65) | 1.62 (0.81–3.25) | 2.36 (1.24–4.51) |
| Financial burden | 2.22 (0.99–4.97) | 1.97 (0.96–4.04) | 4.10 (2.10–8.03) |
| Ability to work | 1.17 (0.42–3.22) | 1.41 (0.56–3.53) | 1.76 (0.75–4.16) |
| Mood | 1.42 (0.59–3.44) | 1.64 (0.74–3.63) | 1.75 (0.83–3.68) |
| ADLs | 1.94 (0.72–5.23) | 2.40 (0.97–5.90) | 2.55 (1.08–6.01) |
| Memory and concentrationa | 2.13 (0.86–5.28) | 2.55 (1.12–5.83) | 2.82 (1.29–6.18) |
| Relationships | 2.14 (0.76–6.08) | 1.83 (0.70–4.81) | 2.06 (0.83–5.14) |
| Diet | 2.46 (0.84–7.21) | 2.71 (1.00–7.37) | 4.28 (1.64–11.2) |
| Parotid swelling, n = 1083 | |||
| Challenge and burdena | 1.52 (1.12–2.06) | 1.93 (1.30–2.87) | 1.98 (1.35–2.91) |
| Functional interference | 1.98 (1.38–2.85) | 2.66 (1.60–4.42) | 2.53 (1.56–4.12) |
| Financial burden | 2.09 (1.46–3.00) | 1.58 (1.02–2.43) | 2.45 (1.55–3.86) |
| Ability to work | 1.60 (1.10–2.33) | 1.95 (1.15–3.28) | 1.84 (1.11–3.06) |
| Mood | 1.25 (0.92–1.70) | 1.34 (0.91–1.98) | 1.37 (0.93–2.02) |
| ADLs | 1.46 (1.07–1.99) | 1.52 (1.03–2.24) | 1.66 (1.13–2.43) |
| Memory and concentrationa | 1.51 (1.11–2.05) | 1.70 (1.15–2.51) | 1.77 (1.21–2.59) |
| Relationships | 1.83 (1.32–2.54) | 1.79 (1.18–2.70) | 2.15 (1.43–3.22) |
| Diet | 1.56 (1.16–2.11) | 2.41 (1.65–3.53) | 1.70 (1.17–2.47) |
| Oral candidiasis, n = 756 | |||
| Challenge and burdena | 4.27 (2.68–6.80) | 3.25 (1.51–7.01) | 2.24 (1.30–3.86) |
| Functional interference | 1.80 (1.12–2.90) | 1.86 (0.80–4.31) | 2.26 (1.16–4.39) |
| Financial burden | 2.97 (1.79–4.94) | 9.58 (2.28–40.3) | 2.07 (1.14–3.77) |
| Ability to work | 1.83 (1.11–3.02) | 2.51 (0.99–6.34) | 4.25 (1.97–9.16) |
| Mood | 1.37 (0.93–2.04) | 1.91 (0.97–3.76) | 1.71 (1.01–2.90) |
| ADLs | 1.88 (1.27–2.78) | 2.66 (1.34–5.24) | 1.71 (1.02–2.87) |
| Memory and concentrationa | 1.41 (0.95–2.09) | 2.66 (1.31–5.40) | 2.54 (1.49–4.31) |
| Relationships | 1.70 (1.12–2.58) | 3.15 (1.58–6.29) | 2.54 (1.49–4.34) |
| Diet | 3.49 (2.36–5.15) | 4.18 (2.07–8.44) | 2.09 (1.25–3.51) |
| Sialolithiasis/infection, n = 434 | |||
| Challenge and burdena | 2.05 (1.11–3.77) | 6.85 (1.54–30.6) | 10.8 (2.52–46.6) |
| Functional interference | 2.62 (1.16–5.92) | 2.82 (0.63–12.6) | 10.2 (1.36–76.1) |
| Financial burden | 3.10 (1.37–7.02) | 3.92 (0.87–17.6) | 2.53 (0.85–7.57) |
| Ability to work | 2.12 (1.04–4.35) | 2.73 (0.64–11.7) | 6.18 (1.66–23.0) |
| Mood | 1.89 (1.07–3.32) | 4.92 (1.65–14.7) | 1.89 (0.81–4.40) |
| ADLs | 2.45 (1.38–4.35) | 6.39 (2.01–20.3) | 2.39 (1.03–5.52) |
| Memory and concentrationa | 1.90 (1.06–3.43) | 9.83 (2.16–44.7) | 1.68 (0.72–3.92) |
| Relationships | 1.54 (0.83–2.85) | 12.3 (3.84–39.4) | 3.58 (1.53–8.36) |
| Diet | 1.61 (0.92–2.80) | 5.62 (1.79–17.7) | 3.70 (1.55–8.82) |
| Tooth decay, n = 1747 | |||
| Challenge and burdena | 1.31 (0.95–1.80) | 3.35 (1.96–5.74) | 2.48 (1.87–3.29) |
| Functional interference | 1.09 (0.78–1.52) | 3.05 (1.58–5.90) | 2.02 (1.47–2.76) |
| Financial burden | 2.28 (1.60–3.25) | 3.62 (1.97–6.64) | 3.35 (2.43–4.62) |
| Ability to work | 1.59 (1.05–2.39) | 1.55 (0.82–2.91) | 1.52 (1.06–2.18) |
| Mood | 1.36 (0.96–1.91) | 2.56 (1.57–4.20) | 1.89 (1.42–2.50) |
| ADLs | 1.93 (1.38–2.70) | 2.74 (1.67–4.48) | 2.41 (1.83–3.18) |
| Memory and concentrationa | 1.92 (1.39–2.67) | 2.14 (1.30–3.53) | 2.57 (1.94–3.39) |
| Relationships | 1.97 (1.37–2.84) | 3.33 (1.98–5.58) | 2.42 (1.79–3.28) |
| Diet | 2.04 (1.47–2.83) | 2.55 (1.57–4.13) | 2.61 (1.98–3.44) |
All models are adjusted for age, sex, race, and employment status. Values in bold are statistically significant (P < 0.05). Referent value = never.
↵aComposite score. ADLs: activities of daily living; SS: Sjögren syndrome.