Table 1.

Patient characteristics.

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Reason for HCQ startTendinitisArthritisArthritisArthritisArthritisArthritisArthritisCLEArthritis
SexFFMFMMFMF
Age, yrs292668555641303759
Disease duration, mos2396213241312
Simultaneous start of NSAIDNoYesYesNoNoYesYesNoYes
No. ACR criteria333242333
No. SLICC criteria233243433
Sum score, EULAR/ACR criteria17131261689108
Clinical criteria
    Skinxxx
    Ulcers
    Synovitisxxxxxx
    Hematologicx
    Serositisx
    Renal
    Neurologic
Immunologic criteria
    ANAxxxxxxxxx
    Anti-dsDNAxxx
    Anti-SSAxxx
    Anti-Smx
    Anti-RNP1x
    Low complementx
    Antiphospholipidsxxx
HCQ serum level, μg/L628147342564315233258129496
Resolution of symptomsNoNoNoNoYesYesNoYesYes
SLEDAI before HCQspecified04a6a,b4a6a,c4a6a,c2d4a
SLEDAI after HCQspecified01e2b4a002c2d0
  • Specification of SLEDAI score:

  • aarthritis (4 points);

  • banti-dsDNA (2 points);

  • clow complement 3 or 4 (2 points);

  • dskin rash (2 points);

  • eleukopenia (1 point). ACR: American College of Rheumatology; ANA: antinuclear antibody; CLE: cutaneous lupus erythematosus; EULAR; European League Against Rheumatism; HCQ: hydroxychloroquine; NSAID: nonsteroidal antiinflammatory drug; SLICC: SLE International Collaborating Clinics; SLEDAI: Systemic Lupus Erythematosus Disease Activity Index.