Characteristics | Patients With SLE Who Met SLICC 2012 but Not EULAR/ACR 2019, n = 18 | Patients With SLE Who Met EULAR/ACR 2019 but Not SLICC 2012, n = 8 | P |
---|---|---|---|
Sex, female | 14 (77.8) | 7 (87.5) | > 0.99 |
Age at diagnosis, months, median (min–max) | 183.5 (96–215) | 156 (62–204) | 0.24 |
Fever (> 38.3°C) | 1 (5.6) | 1 (12.5) | 0.52 |
Pleuritis | 0 (0) | 1 (12.5) | 0.30 |
Pericarditis | 0 (0) | 1 (12.5) | 0.30 |
Joint involvement | 3 (16.7) | 6 (75) | 0.008 |
Nonscarring alopecia | 2 (11.1) | 0 (0) | > 0.99 |
Oral ulcers | 8 (44.4) | 0 (0) | 0.03 |
Malar rash | 5 (27.8) | 4 (50) | 0.38 |
Discoid rash | 3 (16.7) | 0 (0) | > 0.99 |
Photosensitivity | 6 (33.3) | 2 (25) | > 0.99 |
Delirium | 1 (5.6) | 0 (0) | > 0.99 |
Psychosis | 1 (5.6) | 0 (0) | > 0.99 |
Focal neurologic defect | 1 (5.6) | 0 (0) | > 0.99 |
Acute confusional state | 1 (5.6) | 0 (0) | > 0.99 |
Leukopenia (< 4000/mm3) | 7 (38.9) | 0 (0) | 0.06 |
Lymphopenia (< 1000/mm3) | 2 (11.1) | 0 (0) | > 0.99 |
Lymphopenia (< 1500/mm3) | 7 (38.9) | 1 (12.5) | 0.36 |
Thrombocytopenia (< 100,000/mm3) | 8 (44.4) | 0 (0) | 0.03 |
Evidence of hemolysis | 5 (27.8) | 0 (0) | 0.28 |
Hematologic involvement | 13 (72.2) | 1 (12.5) | 0.009 |
Proteinuria | 3 (16.7) | 0 (0) | 0.52 |
Low C3 | 3 (16.7) | 1 (12.5) | > 0.99 |
Low C4 | 8 (44.4) | 1 (12.5) | 0.19 |
ANA positivity (≥ 1/80) | 15 (83.3) | 8 (100) | 0.52 |
Anti-dsDNA | 1 (5.6) | 3 (37.5) | 0.07 |
Anti-Sm | 0 (0) | 1 (12.5) | 0.31 |
Anticardiolipin antibodies | 6 (33.3) | 0 (0) | 0.26 |
Anti-β2-GPI | 3 (16.7) | 0 (0) | 0.50 |
Lupus anticoagulant | 3 (16.7) | 0 (0) | 0.52 |
Direct Coombs | 6 (33.3) | 0 (0) | 0.14 |
Biopsy-proven LN | 3 (16.7) | 0 (0) | 0.52 |
SLE according to the ACR 1997 criteria | 7 (38.9) | 2 (25) | > 0.99 |
Values are expressed as n (%) unless stated otherwise. ACR: American College of Rheumatology; ANA: antinuclear antibody; anti-β2-GPI: anti-β2-glycoprotein I; EULAR: European League Against Rheumatism; LN: lupus nephritis; SLE: systemic lupus erythematosus; SLICC: Systemic Lupus International Collaborating Clinics.