Table 3.

Linear regression analyses of the HLA genetic risk scores (GRS).

Genetic Risk Counting ScoresGenetic Risk Weighted Scores
GRCSGRSCSGRWSGRSWS
Final model P value*0.0490.0220.0220.011
Slopea0.0140.0130.0260.014
Adjusted r20.1760.1760.1760.177
  • *Final model of all HLA GRS includes sex and all 4 ancestral populations as covariates.

  • aSlope represents the rate of change in y (age of diagnosis) as x (HLA GRS) changes. Values in bold are statistically significant. GRCS: genetic risk counting score; GRSCS: genetic risk standardized counting score; GRWS: genetic risk weighted score; GRSWS: genetic risk standardized weighted score.