Table 2.

Mean differences in key outcome measures between while subjects were on creatine compared to on placebo.

Mean DifferenceP
Peak power, watts9.50.77
Fatigue index, %1.090.77
Total MET–1.241
MVPA, no. 30-min blocks0.110.87
VPA, no. 30-min blocks–0.570.16
CHAQ (/3)0.0050.81
Illness rating (/100)–2.600.24
Pain rating (/100)–0.260.93
PedsQL Fatigue Index (/100)3.60.98
Right hand grip, kg–0.260.91
Left hand grip, kg–0.900.62
Max jump, inches–0.210.82
Physician global assessment (/100)1.310.64
Patient global assessment (/100)–0.560.89
MMT-8 (/80)0.810.59
CMAS (/52)–0.080.88
Muscle disease activity (/100)–0.250.78
Global disease activity (/100)1.240.69
Overall QoML (/100)3.030.64
Health-related QOL (/100)1.600.13
YMCA-estimated peak VO20.840.37
Body fat, %0.010.99
Waist circumference, cm1.510.05
  • CHAQ: Childhood Health Assessment Questionnaire; CMAS: Childhood Myositis Assessment Scale; MET: metabolic equivalents; MMT: manual muscle testing; MVPA: moderate to vigorous physical activity; PedsQL: Pediatric Quality of Life; QOL: quality of life; QoML: Quality of My Life; VPA: vigorous physical activity.