Table 4.

31P-MRS exercise testing results at baseline (B) and end-of-study (E) for each of the 3 exercise tests: 30 seconds at maximal intensity, 60 seconds at moderate intensity, and 5 × 30 seconds at moderate intensity each separated by 15 seconds of rest.

Timepoint30-s Test, mean ± SDP60-s Test, mean ± SDP5 × 30-s Test, mean ± SDP
Change in pH afer exerciseB0.32 ± 0.280.570.46 ± 0.260.960.30 ± 0.270.003
(rest pH-end exercise pH)E0.37 ± 0.430.45 ± 0.300.25 ± 0.26
Pi/PCr, ratioB1.30 ± 0.610.112.44 ± 1.200.032.48 ± 1.580.28
E1.17 ± 0.702.08 ± 1.122.33 ± 1.99
ATP produced by creatineB0.31 ± 0.100.080.20 ± 0.040.250.34 ± 0.110.11
  kinase, mmol/L/min–1E0.29 ± 0.120.19 ± 0.060.31 ± 0.13
ATP produced by anaerobicB0.69 ± 0.530.590.57 ± 0.330.230.92 ± 0.700.01
  glycolysis, mmol/L/min–1E0.65 ± 0.530.52 ± 0.330.80 ± 0.69
ATP produced by aerobicB0.30 ± 0.070.040.34 ± 0.140.240.23 ± 0.070.69
  oxidation, mmol/L/min–1E0.23 ± 0.110.31 ± 0.160.21 ± 0.08
ATP total produced by allB1.30 ± 0.640.131.11 ± 0.410.101.48 ± 0.820.02
  pathways, mmol/L/min–1E1.17 ± 0.751.02 ± 0.481.33 ± 0.84
  • 31P-MRS: 31-Phosphorus Magnetic Resonance Spectroscopy; ATP: adenosine triphosphate; PCr: phosphocreatine; Pi: phosphate.