Variable | Baseline, mean ± SD | End-of-study, mean ± SD | P |
---|---|---|---|
Resting PCr | 18.86 ± 0.62 | 19.23 ± 0.68 | 0.12 |
Resting Pi | 1.93 ± 0.20 | 1.82 ± 0.17 | 0.21 |
Resting ATP | 20.51 ± 0.63 | 20.25 ± 0.67 | 0.21 |
Resting pH | 6.96 ± 0.02 | 6.96 ± 0.02 | 0.33 |
Resting Pi/PCr, ratio | 0.10 ± 0.01 | 0.09 ± 0.01 | 0.16 |
While none of the variables had changes that were statistically significant, there was a weak signal toward an increase in PCr at rest at the end-of-study. 31P-MRS: 31-Phosphorus Magnetic Resonance Spectroscopy; ATP: adenosine triphosphate; PCr: phosphocreatine; Pi: phosphate.