Table 1.

Demographic, histopathologic, and initial renal function characteristics of the patients.

Values
Sex, female:male8:2
Age at LN diagnosis, yrs34.2 ± 7.3
Disease duration, yrs2.2 ± 2.5
Race/ethnicity, n
      Black5
      Hispanic2
      White2
      Asian1
LN histopathologic class
      III1
      IV5
      IV/V2
      V2
Activity index5.7 ± 4.9
Chronicity index3.3 ± 3.0
Serum creatinine, μmol/L82.1 ± 15.5
eGFR, mL/min/1.73 m290.2 ± 24.9
Anemia, n (%)a3 (30%)
Proteinuria, g/24 h2.7 ± 1.04
Nephrotic syndrome, n (%)5 (50%)
Serum albumin, g/L32.5 ± 3.7
Hypertension, n (%)b5 (50%)
Time to ESKD, months19.2 ± 12.4
Rate of renal function decline, mL/min/1.73 m2/yr, median43.3

  • ↵aDefined as hemoglobin < 120 g/L for females and < 130 g/L for males.

  • ↵bDefined as blood pressure > 130/80 mmHg. eGFR: estimated glomerular filtration rate; ESKD: endstage kidney disease; LN: lupus nephritis.