Hypothetical maximal flare occurrence for each disease state.
| Time Horizon | Disease State | No. Flares, Median (IQR) | P* |
|---|---|---|---|
| No. flares over 6 months | Remission | 0 (0–0) | < 0.001 |
| LDA | 1 (0–2) | ||
| PASS | 0 (0–1) | ||
| No. flares over 12 months | Remission | 0 (0–0) | < 0.001 |
| LDA | 1 (0–2) | ||
| PASS | 0 (0–2) |
↵* From related samples Friedman 2-way ANOVA by ranks (all pairwise comparisons were also statistically significant). LDA: low disease activity; PASS: patient acceptable symptom state.