Disease Activity (Composite Index) | HRQOL (PROM) | Rate of Agreement on Treatment Continuation, n = 97‡ | ||
---|---|---|---|---|
Profile A†, % | Profile B†, % | Profile C†, % | ||
Remission | Optimal | 100* | 100* | 100* |
Remission | Suboptimal with CII | 99.0* | 99.0* | 99.0* |
Remission | Suboptimal without CII | 61.9 | 78.4* | 88.7* |
Low activity | Optimal | 95.9* | 97.9* | 97.9* |
Low activity | Suboptimal with CII | 89.7* | 95.9* | 97.9* |
Low activity | Suboptimal without CII | 25.8 | 47.4 | 75.3* |
Moderate/high activity with CII | Optimal | 61.9 | 67.0 | 82.5* |
Moderate/high activity with CII | Suboptimal with CII | 40.2 | 51.5 | 72.2 |
Moderate/high activity with CII | Suboptimal without CII | 7.2 | 10.3 | 29.9 |
Moderate/high activity without CII | Optimal | 10.3 | 15.5 | 27.8 |
Moderate/high activity without CII | Suboptimal with CII | 6.2 | 8.2 | 10.3 |
Moderate/high activity without CII | Suboptimal without CII | 3.1 | 3.1 | 2.1 |
↵‡ Nine participants failed in the test scenario and their responses were subtracted from the analysis.
↵† Patient profile A, naive to biological treatment; patient profile B, without structural damage, and functional disability and/or mild-moderate psoriasis, and failure to 1 biological treatment; patient profile C, with structural damage, serious sequelae, and failure to several biological treatments.
↵* Consensus reached (≥ 75%). HRQOL: health-related quality of life; PROM: patient-reported outcome measures; CII: clinically important improvement.