Table 3.

Minimum health outcomes for treatment continuation.

Disease Activity (Composite Index)HRQOL (PROM)Rate of Agreement on Treatment Continuation, n = 97
Profile A, %Profile B, %Profile C, %
RemissionOptimal100*100*100*
RemissionSuboptimal with CII99.0*99.0*99.0*
RemissionSuboptimal without CII61.978.4*88.7*
Low activityOptimal95.9*97.9*97.9*
Low activitySuboptimal with CII89.7*95.9*97.9*
Low activitySuboptimal without CII25.847.475.3*
Moderate/high activity with CIIOptimal61.967.082.5*
Moderate/high activity with CIISuboptimal with CII40.251.572.2
Moderate/high activity with CIISuboptimal without CII7.210.329.9
Moderate/high activity without CIIOptimal10.315.527.8
Moderate/high activity without CIISuboptimal with CII6.28.210.3
Moderate/high activity without CIISuboptimal without CII3.13.12.1
  • Nine participants failed in the test scenario and their responses were subtracted from the analysis.

  • Patient profile A, naive to biological treatment; patient profile B, without structural damage, and functional disability and/or mild-moderate psoriasis, and failure to 1 biological treatment; patient profile C, with structural damage, serious sequelae, and failure to several biological treatments.

  • * Consensus reached (≥ 75%). HRQOL: health-related quality of life; PROM: patient-reported outcome measures; CII: clinically important improvement.