Predictors (variables present at baseline) for progression of CKD.
| Variables | HR | Lower 95% CI | Higher 95% CI | p |
|---|---|---|---|---|
| Univariate analysis | ||||
| Age | 0.967 | 0.943 | 0.991 | 0.007 |
| Proliferative LN (III + IV) | 2.223 | 1.192 | 4.145 | 0.012 |
| SLEDAI-2K | 1.049 | 1.003 | 1.098 | 0.038 |
| eGFR | 0.929 | 0.898 | 0.962 | < 0.001 |
| Anti-dsDNA + low C3/C4 | 2.926 | 1.603 | 5.34 | < 0.001 |
| Hb < 12g/l | 2.334 | 1.264 | 4.309 | 0.007 |
| Antimalarial treatment | 1.98 | 1.089 | 3.601 | 0.025 |
| CKD 4 (compared to CKD 3b) | 2.487 | 1.379 | 4.486 | 0.003 |
| Multivariate analysis | ||||
| Anti-dsDNA + low C3/C4 | 2.72 | 1.41 | 5.24 | 0.003 |
| CKD 4 (compared to CKD 3b) | 2.76 | 1.5 | 5.08 | 0.001 |
CKD: chronic kidney disease; LN: lupus nephritis; SLEDAI-2K: Systemic Lupus Erythematosus Disease Activity Index 2000; eGFR: estimated glomerular filtration rate; Hb: hemoglobin.