Table 3.

HR of diabetes mellitus in patients with juvenile idiopathic arthritis (JIA) compared to the healthy population and patients with asthma.

JIA vs AsthmaJIA vs Healthy Children
Age, Sex, Index Date-matched HR (95% CI)Fully Adjusted HR* (95% CI)Age, Sex, Index Date-matched HR (95% CI)Fully Adjusted HR* (95% CI)
Primary outcome
  Type 1 diabetes1.46 (0.87–2.44)1.48 (0.86–2.56)1.89 (1.11–3.19)1.81 (1.03–3.17)
Secondary outcome
  Type 2 diabetes0.95 (0.64–1.43)1.01 (0.66–1.54)1.33 (0.88–2.02)1.22 (0.79–1.90)
Composite diabetes1.11 (0.77–1.60)1.18 (0.80–1.73)1.52 (1.05–2.21)1.40 (0.94–2.09)
  • * The full model included age, sex, index date, region, calendar year (continuous), hyperlipidemia, hypertension, obesity, inhalation steroid dose, cumulative steroid dose (prednisone-dose equivalent) in the 365 days prior to index date, emergency room visit, and hospitalization.