Characteristic | Healthy Children, n = 76,050 | Asthma Cohort, n = 76,050 | JIA Cohort, n = 15,210 |
---|---|---|---|
Demographic features | |||
Age, yrs, mean (SD) | 13.86 (3.44) | 13.86 (3.44) | 13.86 (3.44) |
Female, % | 67.28 | 67.28 | 67.28 |
Comorbidities, % | |||
Hyperlipidemia | 0.58 | 1.09 | 1.26 |
Hypertension | 0.42 | 0.69 | 1.04 |
Obesity | 1.70 | 2.69 | 2.01 |
Previous medications, % | |||
NSAID | 6.74 | 10.25 | 65.71 |
Inhaled corticosteroids | 7.01 | 57.15 | 15.31 |
Oral steroids (past 30 days) | 1.01 | 24.25 | 28.28 |
Oral steroids (past 365 days) | 6.66 | 40.49 | 39.98 |
Cumulative steroid dose, mean (SD) mg* | 31.45 (379.77) | 301.15 (2738.23) | 454.90 (2612.21) |
Healthcare use | |||
Emergency visit, % | 12.69 | 29.26 | 27.94 |
Hospitalization, % | 1.58 | 5.11 | 7.17 |
Total no. drugs prescribed, mean ± SD | 2.22 ± 2.69 | 6.09 ± 3.94 | 6.53 ± 4.63 |
HbA1c test performed, % | 1.42 | 2.31 | 2.79 |
↵* Cumulative prednisone-equivalent dose of oral steroids prescribed 365 days prior to index date. JIA: juvenile idiopathic arthritis; NSAID: nonsteroidal antiinflammatory drugs; HbA1c: hemoglobin A1c.