Baseline and followup demographics in 195 patients with incident ANCA-associated vasculitis.
| Characteristics | N = 195 (%) |
|---|---|
| Sex | |
| Male | 97 (50) |
| Female | 98 (50) |
| Age, yrs | 69 (55–77) |
| Age quartiles, yrs | |
| 0–55 | 49 (25) |
| 55–70 | 57 (29) |
| 70–80 | 53 (27) |
| 80–100 | 36 (18) |
| P creatinine, µmol/l | 152 (75–319) |
| eGFR, ml/min | 40 (15–80) |
| CKD groups | |
| CKD 1–2 | 74 (38) |
| CKD 3 | 38 (19) |
| CKD 4 | 36 (18) |
| CKD 5 | 47 (24) |
| B hemoglobin, g/l | 110 (96–123) |
| Platelets, 109/l | 366 (283–450) |
| CRP, mg/l | 87 (22–142) |
| ANCA | |
| PR3 | 100 (51) |
| MPO | 84 (43) |
| Negative | 11 (6) |
| Diagnosis | |
| GPA | 94 (48) |
| MPA | 90 (46) |
| EGPA | 11 (6) |
| Renal transplantation | 7 (4) |
| Previous malignancy | 16 (8) |
| Followup, yrs | 8.0 (4.0–11.9) |
| Deaths | 98 (50) |
| CYC < 1 g | 30 (15) |
| CYC 1–10 g | 82 (42) |
| CYC > 10 g | 83 (42) |
| CYC > 36 g | 14 (7) |
Data are presented in n (%) and median (IQR). ANCA: antineutrophil cytoplasmic antibodies; eGFR: estimated glomerular filtration rate; CKD: chronic kidney disease; CRP: C-reactive protein; PR3: proteinase 3; MPO: myeloperoxidase; GPA: granulomatosis with polyangiitis; MPA: microscopic polyangiitis; EGPA: eosinophilic GPA; CYC: cyclophosphamide; IQR: interquartile range.