Relationship of patient-level factors to prior use of NSAID: results of logistic regression modeling.
| Independent Variables | Dependent Variable: Used NSAID | |
|---|---|---|
| Unadjusted OR (95% CI) | Adjusted OR (95% CI)* | |
| Age, per yr increase | 0.95 (0.93–0.96) | 0.97 (0.94–0.99) |
| Male sex (ref. female) | 0.72 (0.55–0.93) | 0.68 (0.48–0.94) |
| < Post-secondary education (ref. post-secondary) | 0.75 (0.58–0.97) | 0.83 (0.60–1.14) |
| Not employed full time (ref. employed) | 0.53 (0.39–0.71) | 0.80 (0.53–1.20) |
| Annual income < $60,000 (ref. ≥ $60,000) | 0.75 (0.59–0.96) | 0.91 (0.64–1.30) |
| Lubben Social Network Score, per unit increase | 0.99 (0.96–1.01) | 0.98 (0.95–1.01) |
| BMI, per unit increase | 1.02 (1.00–1.04) | 1.00 (0.97–1.02) |
| Heart disease | 0.50 (0.39–0.71) | 0.70 (0.45–1.06) |
| Hypertension | 0.81 (0.62–1.06) | 1.05 (0.76–1.43) |
| Diabetes | 0.58 (0.42–0.81) | 0.69 (0.46–1.05) |
| Kidney disease | 0.37 (0.18–0.76) | 0.45 (0.20–1.04) |
| Gastrointestinal disease | 1.14 (0.75–1.74) | 1.37 (0.80–2.34) |
| PHQ-8, per 1 unit | 1.00 (0.98–1.03) | 0.98 (0.95–1.02) |
| WOMAC pain, per 1 unit | 1.03 (0.99–1.07) | 0.99 (0.93–1.06) |
| KOOS-PS, per 1 unit | 1.01 (1.00–1.02) | 1.01 (0.99–1.02) |
| Perceived OA coping efficacy, per 1 unit | 1.00 (0.96–1.03) | 0.97 (0.93–1.04) |
↵* Model: goodness-of-fit p = 0.55; C-statistic = 0.67. Bold face denotes statistical significance (p < 0.05). BMI: body mass index; OA: osteoarthritis; WOMAC: Western Ontario and McMaster Universities Osteoarthritis Index; KOOS-PS: Knee Injury and Osteoarthritis Outcome Score Physical Function Short Form; NSAID: nonsteroidal antiinflammatory drug; PHQ-8: 8-item Patient Health Questionnaire Depression Scale.