Table 2.

OR (95% CI) for the association of sleep quality, a single item from the Pittsburgh Sleep Quality Index (PSQI) with knee pain outcomes stratified by baseline widespread pain status.

Knee Pain OutcomesSleep Quality in Past Week in the PSQI
0, 1 = Poor (Ref.)2 = Fairly Good3 = Very GoodP Trend
Consistent frequent knee pain
  Cross-sectional association for prevalent consistent frequent knee pain, n = 4640
    Knee, n/N (%)1376/824 (45.6)887/2582 (34.4)342/1234 (27.7)
    OR (95% CI)21.0 (ref)0.84 (0.68–1.03)0.69 (0.54–0.90)0.005
Longitudinal association for incident consistent frequent knee pain, n = 2646
    Knee, n/N (%)88/385 (17.6)309/1503 (61.7)104/758 (20.8)
    OR (95% CI)1.0 (ref)1.07 (0.84–1.36)0.80 (0.60–1.07)0.08
Knee pain worsening, n = 4658
  Widespread pain absence, n = 2746
    Knee, n/N (%)87/358 (24.3)304/1476 (20.6)159/912 (17.4)
    OR (95% CI)1.0 (ref)0.86 (0.62–1.21)0.70 (0.48–1.02)0.037
  Widespread pain presence, n = 1912
    Knee, n/N (%)176/470 (37.4)359/1116 (32.1)87/326 (26.7)
    OR (95% CI)1.0 (ref)0.72 (0.54–0.96)0.53 (0.35–0.78)< 0.01
  • 1 No. knees: n (knees with pain worsening or incident joint pain) / N (total no. knees).

  • 2 Model adjusted for age (yrs), sex (men vs women), race (white vs non-white), study site, BMI (kg/m2), education level (college and above vs below college), tobacco use (pack-yrs), Charlson Comorbidity Index (range 0–9), fatigue (10-point scale), CES-D depression indicator (yes, no), and prescription use of NSAID (yes, no). BMI: body mass index; CES-D: Center for Epidemiologic Studies Depression Scale; NSAID: nonsteroidal antiinflammatory drug.