Targeted approaches to blocking inflammatory cytokines in cytokine storm syndrome.
| Inflammatory Cytokine | Therapeutic | Reference |
|---|---|---|
| IL-1 | Anakinra | 11 |
| IL-6 | Tocilizumab | 16 |
| IL-18 | Tadekinig alpha | 26 |
| IFN-γ | Emapalumab | 27 |
| IL-6, IFN-γ, others | Ruxolitinib | 28 |
| TNF | Infliximab | 29 |
IL: interleukin; IFN: interferon; TNF: tumor necrosis factor.