Table 2.

Targeted approaches to blocking inflammatory cytokines in cytokine storm syndrome.

Inflammatory CytokineTherapeuticReference
IL-1Anakinra11
IL-6Tocilizumab16
IL-18Tadekinig alpha26
IFN-γEmapalumab27
IL-6, IFN-γ, othersRuxolitinib28
TNFInfliximab29
  • IL: interleukin; IFN: interferon; TNF: tumor necrosis factor.