DAS28-CRP intra- and interrater reliability.
| Variables | Intrarater Reliability (PP) | n | Interrater Reliability (CC) | |||||||
|---|---|---|---|---|---|---|---|---|---|---|
| n | Situation 1 † ICC (95% CI) | MDC | n | Situation 2 †† ICC (95% CI) | MDC | Pt vs HCP1, ICC (95% CI) | Pt vs HCP2, ICC (95% CI) | HCP1 vs HCP2, ICC (95% CI) | ||
| Visit 1§, all (primary) | 121 | 0.87 (0.80–0.91) | 1.12 | 187 | 0.87 (0.83–0.90) | 1.13 | 60 | 0.75 (0.61–0.84) | 0.79 (0.68–0.87) | 0.86 (0.78–0.91) |
| Visit 3§, all | 121 | 0.93 (0.90–0.95) | 0.92 | 187 | 0.92 (0.90–0.94) | 1.00 | 46 | 0.86 (0.71–0.93) | 0.87 (0.75–0.93) | 0.90 (0.82–0.94) |
| Visit 3§, subgroup A | 67 | 0.94 (0.90–0.96) | 0.84 | 102 | 0.93 (0.90–0.96) | 0.92 | 25 | 0.87 (0.71–0.94) | 0.87 (0.72–0.94) | 0.90 (0.78–0.95) |
| Visit 3§, subgroup B | 54 | 0.92 (0.87–0.95) | 1.00 | 85 | 0.91 (0.86–0.94) | 1.08 | 21 | 0.81 (0.47–0.93) | 0.84 (0.63–0.93) | 0.87 (0.71–0.95) |
| Visit 1 pretraining‡, all | 121 | 0.88 (0.84–0.92) | 1.04 | 187 | 0.90 (0.87–0.92) | 0.99 | 60 | 0.69 (0.51–0.84) | 0.74 (0.59–0.84) | 0.86 (0.78–0.91) |
↵† Situation 1: assessment of intrarater reliability in the PP population with short time followup performed within 1–3 days.
↵†† Situation 2: assessment of intrarater reliability in the PP population with short time followup performed within 1–7 days.
↵§ For intrarater reliability, visit 1 is compared with visit 2, and visit 3 is compared with visit 4.
↵‡ For intrarater reliability, visit 1 pretraining is compared to visit 1 post-training. DAS28-CRP: 28-joint count Disease Activity Score using C-reactive protein; ICC: intraclass correlation coefficient; MDC: minimal detectable change; PP: per-protocol population; CC: complete-case population; Pt: patient; HCP1: healthcare professional (experienced rheumatologist); HCP2: medical student trained in joint assessments.