New CV events in RA and DM versus the reference population.
| Patients | HR | 95% CI | p |
|---|---|---|---|
| All patients | |||
| Model 1 | |||
| Nondiabetic population | 1.00 | Reference | — |
| DM | 1.51 | 1.02–2.22 | 0.04 |
| Nondiabetic patients with RA | 2.07 | 1.57–2.72 | < 0.01 |
| Model 2 | |||
| Nondiabetic population | 1.00 | Reference | — |
| DM | 1.28 | 0.85–1.92 | 0.25 |
| Nondiabetic patients with RA | 1.82 | 1.32–2.50 | < 0.01 |
| Patients with prevalent CVD excluded | |||
| Model 1 | |||
| Nondiabetic population | 1.00 | Reference | — |
| DM | 1.42 | 0.92–2.21 | 0.12 |
| Nondiabetic patients with RA | 1.82 | 1.32–2.50 | < 0.01 |
| Model 2 | |||
| Nondiabetic population | 1.00 | Reference | — |
| DM | 1.15 | 0.72–1.84 | 0.56 |
| Nondiabetic patients with RA | 1.96 | 1.39–2.78 | < 0.01 |
Model 1: adjusted for age and sex. Model 2: adjusted for age, sex, systolic blood pressure, antihypertensive agents, total cholesterol, high-density lipoprotein cholesterol, statins, smoking in pack-years, body mass index, and aspirin. CV: cardiovascular; CVD: CV disease; RA: rheumatoid arthritis; DM: type 2 diabetes mellitus.