Table 3.

Interferon-regulated gene expression categorized by unsupervised hierarchical clustering among subjects with primary Sjögren syndrome, some with a focus score (FS) > 1 on minor salivary gland pathology and some with a focus score of zero.

Interferon-regulated Gene Expression
HighIntermediateLow
Anti-Ro, FS = 0, n = 60*24
Anti-Ro, FS ≥ 1, n = 4731155
  • All subjects had anti-Ro. Gene expression analysis was performed on a random sample from subjects with FS = 0 and FS > 1.

  • * p = 0.001 comparing high versus low/intermediate.

  • p = 0.02 comparing distribution across high, intermediate, and low interferon-regulated gene expression.