Characteristics | RA Population | Reference Population | p |
---|---|---|---|
All patients, n | 326 | 1869 | |
Total followup, yrs | 2973 | 18,874 | |
Fatal and nonfatal CV events, n | 95 | 257 | |
Incidence per 100 person-yrs | 3.20 | 1.36 | |
HR RA vs reference cohort | |||
Model 1* | 1.93 (1.51–2.45) | 1.00 | < 0.01 |
Model 2# | 1.89 (1.40–2.46) | 1.00 | < 0.01 |
Patients with prevalent CVDΔ excluded, n | 278 | 1746 | |
Total followup, yrs | 2627 | 18,008 | |
Fatal and nonfatal CV event, n | 69 | 225 | |
Incidence per 100 person-yrs | 2.63 | 1.25 | |
HR RA vs reference cohort | |||
Model 1* | 1.75 (1.31–2.32) | 1.00 | < 0.01 |
Model 2# | 1.96 (1.45–2.66) | 1.00 | < 0.01 |
↵* Adjusted for age and sex.
↵# Adjusted for age, sex, systolic blood pressure, antihypertensive agents, total cholesterol, high-density lipoprotein cholesterol, statins, smoking in pack-years, body mass index, diabetes mellitus, and aspirin.
↵Δ CVD according to the International Classification of Diseases criteria. CV: cardiovascular; RA: rheumatoid arthritis; CVD: CV disease.