Maternal and neonatal outcomes for 312,081 pregnant women in Alberta from January 1, 2005, to December 31, 2014.*
| Characteristics | No IA | RA | SpA** | p |
|---|---|---|---|---|
| Preterm delivery | 21,997 (7.1) | 85 (13.5) | 181 (7.4) | < 0.01 |
| Cesarean delivery | 87,771 (28.4) | 214 (33.9) | 715 (29.1) | < 0.01 |
| Elective cesarean delivery | 37,053 (12.0) | 95 (15.1) | 338 (13.7) | < 0.01 |
| Emergent cesarean delivery | 50,718 (16.4) | 119 (18.9) | 377 (15.3) | 0.09 |
| Induction | 82,415 (26.7) | 182 (28.8) | 722 (29.3) | < 0.01 |
| Mortality within 40 days of birth | 17 (0.0) | 0 (0.0) | 1 (0.0) | 0.07 |
| Hypertensive disorders in pregnancy*** | 19,831 (6.4) | 66 (10.5) | 179 (7.3) | < 0.01 |
| Gestational diabetes | 18,595 (6.0) | 32 (5.1) | 162 (6.6) | 0.3 |
| Birth weight, g, mean (SD) | 3349 (562) | 3224 (597) | 3364 (548) | < 0.01 |
| Small for gestational age | 34,757 (11.3) | 98 (15.6) | 260 (10.6) | < 0.01 |
| Large for gestational age | 27,706 (9.0) | 62 (9.8) | 238 (9.7) | 0.36 |
| Neonatal death within 30 days of birth | 973 (0.3) | 3 (0.5) | 11 (0.4) | 0.39 |
| Congenital anomaly | 5751 (1.9) | 18 (2.9) | 52 (2.1) | 0.12 |
| Mean (SD) days in NICU | 0.8 (5.0) | 1.2 (5.7) | 0.8 (4.5) | 0.14 |
Data are n (%) unless otherwise indicated.
↵* Sensitivity analyses evaluating maternal and neonatal outcomes in primiparous women revealed similar results.
↵** Includes SpA, ankylosing spondylitis, psoriasis, and psoriatic arthritis.
↵*** Includes gestational hypertension, preeclampsia, and eclampsia. IA: inflammatory arthritis; RA: rheumatoid arthritis; SpA: spondyloarthritis; NICU: neonatal intensive care unit.