Joint | DCE-MRI | Remission | Response | dGEMRIC | ||||||
---|---|---|---|---|---|---|---|---|---|---|
E | SE | p | E | SE | p | E | SE | p | ||
MCP2 | ME | −15.6 | 6.7 | 0.02 | −48.5 | 22.5 | 0.03 | −0.8 | 0.2 | < 0.0001 |
MV | −0.5 | 0.2 | 0.01 | −1.3 | 0.8 | 0.09 | −18.1 | 4.9 | < 0.001 | |
RE | −0.3 | 0.2 | 0.04 | −0.9 | 0.6 | 0.11 | −31.5 | 6.3 | < 0.0001 | |
MCP3 | ME | −8.7 | 3.8 | 0.02 | −28.4 | 13.5 | 0.03 | −1.1 | 0.3 | < 0.0001 |
MV | −0.4 | 0.2 | 0.02 | −0.6 | 0.6 | 0.28 | −24.7 | 8.6 | 0.004 | |
RE | −0.3 | 0.1 | < 0.01 | −0.5 | 0.4 | 0.23 | −38.4 | 11.6 | < 0.001 |
Dynamic contrast-enhanced MRI (DCE-MRI) was used to calculate maximum synovial enhancement (ME), maximum synovial volume (MV), and the rate of synovial enhancement (RE) in MCP2 and MCP3 of 28 rheumatoid arthritis patients. DCE-MRI variables were associated with EULAR remission, EULAR good or moderate vs no response, and cartilage quality (dGEMRIC) by linear mixed modeling. MRI: magnetic resonance imaging; dGEMRIC: delayed gadolinium enhancement MRI of cartilage; E: estimate; SE: standard error; MCP: metacarpophalangeal joint; EULAR: European League Against Rheumatism.