Table 1A.

Associations of synovial perfusion imaging with outcome and cartilage quality.

JointDCE-MRIRemissionResponsedGEMRIC
ESEpESEpESEp
MCP2ME−15.66.70.02−48.522.50.03−0.80.2< 0.0001
MV−0.50.20.01−1.30.80.09−18.14.9< 0.001
RE−0.30.20.04−0.90.60.11−31.56.3< 0.0001
MCP3ME−8.73.80.02−28.413.50.03−1.10.3< 0.0001
MV−0.40.20.02−0.60.60.28−24.78.60.004
RE−0.30.1< 0.01−0.50.40.23−38.411.6< 0.001
  • Dynamic contrast-enhanced MRI (DCE-MRI) was used to calculate maximum synovial enhancement (ME), maximum synovial volume (MV), and the rate of synovial enhancement (RE) in MCP2 and MCP3 of 28 rheumatoid arthritis patients. DCE-MRI variables were associated with EULAR remission, EULAR good or moderate vs no response, and cartilage quality (dGEMRIC) by linear mixed modeling. MRI: magnetic resonance imaging; dGEMRIC: delayed gadolinium enhancement MRI of cartilage; E: estimate; SE: standard error; MCP: metacarpophalangeal joint; EULAR: European League Against Rheumatism.