Definition of Remission | Remission, at First METEOR Visit** | Remission, Taking All Visits into Account** | |||
---|---|---|---|---|---|
Yes | No | Yes | No | ||
ACR/EULAR Boolean-based | 182 (88.8) | 1868 (29.3) | 1556 (87.0) | 10,897 (34.1) | |
SDAI ≤ 3.3 | 403 (81.7) | 827 (21.6) | 4011 (78.1) | 5005 (25.7) | |
CDAI ≤ 2.8 | 606 (80.5) | 1364 (25.1) | 4900 (78.5) | 6775 (27.4) | |
DAS-CRP < 1.6 | 4v | 814 (58.6) | 780 (20.5) | 7826 (59.1) | 3253 (19.3) |
3v | 818 (54.5) | 830 (21.1) | 7836 (56.4) | 3583 (20.7) | |
DAS-ESR < 1.6 | 4v | 1191 (60.8) | 1211 (23.1) | 9169 (63.2) | 5105 (22.6) |
3v | 1158 (56.7) | 1314 (24.1) | 8970 (60.4) | 5693 (24.3) | |
DAS28-CRP < 2.6 | 4v | 1056 (64.6) | 994 (20.1) | 8316 (62.8) | 4137 (20.2) |
3v | 1091 (58.8) | 1024 (20.5) | 8512 (57.7) | 4301 (21.3) | |
DAS28-ESR < 2.6 | 4v | 1154 (67.5) | 1863 (25.8) | 8292 (68.1) | 7828 (26.5) |
3v | 1067 (60.5) | 2041 (27.0) | 7711 (62.5) | 8851 (28.7) | |
DAS28-CRP < 1.9* | 4v | 567 (75.3) | 1483 (25.4) | 5002 (74.8) | 7451 (27.6) |
3v | 550 (68.2) | 1565 (25.9) | 4778 (65.8) | 8035 (29.1) | |
DAS28-ESR < 2.2* | 4v | 712 (69.3) | 2305 (29.2) | 5616 (72.3) | 10,504 (30.9) |
3v | 611 (61.1) | 2497 (30.1) | 4921 (64.9) | 11,641 (32.7) | |
DAS28-CRP < 2.4* | 4v | 941 (67.4) | 1109 (21.4) | 7583 (65.5) | 4870 (22.0) |
3v | 978 (61.2) | 1137 (21.6) | 7737 (60.2) | 5076 (23.0) |
Values are n (%).
↵* DAS28 formulae with the newly suggested cutoffs [DAS28-CRP < 1.9 (calculated vs SDAI), DAS28-ESR < 2.2 (calculated vs SDAI), and DAS28-CRP < 2.4 (calculated vs DAS28-ESR)].
↵** Percentages presented in each column are independent (not complementary) of the next-side column. ACR: American College of Rheumatology; EULAR: European League Against Rheumatism; CDAI: Clinical Disease Activity Index; CRP: C-reactive protein; DAS: Disease Activity Score; DAS28: 28-joint count DAS; ESR: erythrocyte sedimentation rate; HAQ: Health Assessment Questionnaire; METEOR: Measurement of Efficacy of Treatment in the Era of Outcome in Rheumatology; SDAI: Simplified Disease Activity Index; 3v: 3 variables; 4v: 4 variables.