CTQ Response | SLE Cases/person-yrs | Model D1, HR (95% CI) | Model D2, HR (95% CI) | SLE Cases/person-yrs | Model E1, HR (95% CI) | Model E2, HR (95% CI) |
---|---|---|---|---|---|---|
None/very low | 8/306,527 | Ref | Ref | 9/271,790 | Ref | Ref |
Low | 17/344,728 | 1.86 (0.80–4.31) | 1.77 (0.76–4.11) | 23/308,528 | 2.25 (1.04–4.88) | 2.12 (0.97–4.61) |
Moderate | 21/417,376 | 1.85 (0.82–4.19) | 1.68 (0.74–3.81) | 19/370,845 | 1.46 (0.66–3.25) | 1.33 (0.60–2.96) |
High | 32/325,999 | 3.31 (1.51–7.22) | 2.71 (1.23–5.95) | 24/291,448 | 2.22 (1.02–4.82) | 1.84 (0.83–4.07) |
p for trend | 0.001 | 0.01 | 0.18 | 0.44 |
Model D1: For subset with depression data available, adjusted for age, race, and parental and childhood factor (maternal and paternal occupation, parental education, parental home ownership, birthweight, age at menarche, somatogram score at age 5 yrs). Model D2: For subset with depression data available, adjusted for age, race, parental and childhood factor, and adult history of depression. Model E1: For subset with PTSD data available, adjusted for age, race, and parental and childhood factor. Model E2: For subset with PTSD data available, adjusted for age, race, paternal and childhood factor, and adult history of PTSD. SLE: systemic lupus erythematosus.