Table 3.

Clinical outcomes of lupus nephritis patients with or without renal thrombotic microangiopathy (TMA).

Clinical OutcomesWith Renal TMA, n = 24Without Renal TMA (controls), n = 48p
CR after 6 mos2 (8.3)3 (6.3)0.743
CR after 12 mos6 (25.0)10 (20.8)0.690
PR after 6 mos2 (8.3)14 (29.2)0.045
PR after 12 mos3 (12.5)16 (33.3)0.070
5-yr patient survival, %87980.127
5-yr renal survival, %70950.023
Median eGFR at last followup, ml/min, IQR50.1 (7–132)85.0 (12–147)0.003
Patients with stage 3 or above CKD at last followup16 (66.6)14 (29.2)0.002
  • Values are n (%) unless otherwise specified. CR: complete remission; PR: partial remission; CKD: chronic kidney disease; eGFR: estimated glomerular filtration rate; IQR: interquartile range.