Anatomical distribution of bone lesions in children with extended and limited chronic nonbacterial osteomyelitis (CNO).
| Anatomical Site | Total, n = 51 | Extended CNO, n = 32 | Limited CNO, n = 19 |
|---|---|---|---|
| Mandibula | 2 (4) | 2 (6) | 0 (0) |
| Clavicula | 12 (24) | 5 (16) | 7 (37) |
| Sternum | 1 (2) | 1 (3) | 0 (0) |
| Scapula | 2 (4) | 2 (6) | 0 (0) |
| Humerus | 3 (6) | 3 (9) | 0 (0) |
| Radius | 3 (6) | 1 (3) | 2 (11) |
| Pelvis* | 17 (33) | 12 (38) | 5 (26) |
| Femur | 22 (43) | 16 (50) | 6 (32) |
| Tibia | 24 (47) | 18 (56) | 6 (32) |
| Fibula | 4 (8) | 4 (13) | 0 (0) |
| Talus | 6 (12) | 4 (13) | 2 (11) |
| Calcaneus | 8 (16) | 8 (25) | 0 (0) |
| Feet (middle foot) | 8 (16) | 7 (22) | 1 (5) |
| Metatarsal bones | 9 (18) | 6 (19) | 3 (16) |
| Feet** | 18 (35) | 14 (44) | 4 (21) |
| SI joint *** | 9 (18) | 7 (22) | 2 (11) |
| Spine | 13 (25) | 11 (34) | 2 (11) |
Anatomical distribution of bone lesions at time of diagnosis was assessed by whole-body magnetic resonance imaging (WB-MRI) and local MRI. Values are no. children (and percentage of children) with bone lesions in each anatomical site.
↵* Not SI joint.
↵** Talus, calcaneus, middle foot, and metatarsal bones.
↵*** All lesions at the SI joints were osseous and synovitis was not described. SI: sacroiliac.