The relationships of health- and disease-related variables assessed at baseline and after 3 years to physical HRQOL (SF-12 PCS) after 19 years (n = 96) #.
| Health- and Disease-related Variables | Univariate Analyses with Baseline Predictors | Multiple Regression Analyses with Baseline Predictors | Univariate Analyses with 3-year Predictors | Multiple Regression Analyses with 3-year Predictors | ||||
|---|---|---|---|---|---|---|---|---|
| B† (95% CI) | p | B† (95% CI) C | p | B† (95% CI) | p | B† (95% CI) C | p | |
| Female sex** | 0.5 (−3.7, 4.7) | 0.81 | −1.8 (−2.3, 5.9) | 0.36 | 0.5 (−3.7, 4.7) | 0.81 | 1.5 (−2.4, 5.3) | 0.46 |
| Age at followup, yrs | 0.2 (−0.2, 0.7) | 0.34 | 0.3 (−0.2, 0.7) | 0.22 | 0.2 (−0.2, 0.7) | 0.34 | 0.0 (−0.4, 0.5) | 0.87 |
| PGA (1–5) | −1.8 (−4.0, 0.5) | 0.12 | −2.3 (−4.2, −0.4) | 0.018 | ||||
| Active joints # # | −0.5 (−1.0, −0.1) | 0.030 | −0.6 (1.7–0.2) | 0.014 | −4.7 (−8.6, −0.8) | 0.020 | −3.8 (−7.5, 0.0) | 0.047 |
| Joints with LROM # # | −0.1 (−0.7, 0.5) | 0.75 | −1.9 (−5.9, 2.0) | 0.23 | ||||
| ESR, mm/h | −0.1 (−0.2, 0.0) | 0.020 | −0.1 (−0.3, 0.1) | 0.44 | ||||
| Physical disability (CHAQ ≥ 1) ** | −7.0 (−11.9, −2.1) | 0.006 | −12.5 (−17.9, −7.0) | < 0.001 | −11.7 (−17.4, −6.0) | < 0.001 | ||
| Pain intensity (VAS 0–10) | −1.0 (−1.7, −0.2) | 0.009 | −1.0 (−1.7, −0.2) | 0.009 | −0.5 (−1.3, 0.3) | 0.22 | ||
| Fatigue (VAS 0–10) | −0.6 (−1.3, 0.2) | 0.15 | −0.8 (−1.6, 0.0) | 0.044 | ||||
| Overall well-being (VAS 0–10) | −1.0 (−1.9, −0.1) | 0.025 | −0.8 (−1.7, 0.1) | 0.09 | ||||
↵* Logistic regression analyses.
↵# Linear regression analyses.
↵† B: unstandardized regression coefficient.
↵A Nagelkerke R2 at baseline: 8%, after 3 years: 13%.
↵B R2 at baseline = 18%, after 3 years = 15%.
↵C R2 at baseline = 14%, after 3 years = 22%.
↵** Dichotomized variable.
↵## Total no. at baseline and dichotomized (no. joints with active arthritis = 0) at 3-year followup.
↵4 Discrete numerical variables at baseline and dichotomized (no. joints with active arthritis 0 value of = 0) at 3-year followup. HAQ-DI: Health Assessment Questionnaire–Disability Index; VAS: visual analog scale; HRQOL: health-related quality of life; SF-12: SF-12v2 Health Survey; PCS: physical component summary; PGA: physician’s global assessment of disease activity; LROM: limited range of motion; ESR: erythrocyte sedimentation rate; CHAQ: Childhood Health Assessment Questionnaire; Overall well-being: patient’s global assessment of overall well-being.