Variables | SQOL-F Sum, range 18–108, Adj B (95% CI) | p | Psychosexual, range 7–42, Adj B (95% CI) | p | Sexual and Relationship Satisfaction, range 5–30, Adj B (95% CI) | p | Self–worthlessness, range 3–18, Adj B (95% CI) | p | Sexual Repression, range 3–18, Adj B (95% CI) | p |
---|---|---|---|---|---|---|---|---|---|---|
Demographics | ||||||||||
Age, yrs | −0.04 (−0.18 to 0.09) | 0.521 | 0.02 (−0.12 to 0.08) | 0.689 | 0.06 (0.01–0.13) | 0.099 | −0.03 (0.07–0.01) | 0.189 | −0.05 (−0.10 to 0.01) | 0.014 |
Male | 4.22 (0.85–7.59) | 0.014 | 2.44 (0.06–4.83) | 0.045 | −0.86 (−2.57 to 0.84) | 0.319 | 1.11 (0.13–2.10) | 0.027 | 1.37 (0.30–2.43) | 0.012 |
Living alone | 1.47 (−2.18 to 5.13) | 0.428 | −0.95 (−3.54 to 1.64) | 0.471 | 3.11 (1.26–4.95) | 0.001 | −0.19 (−1.25 to 0.087) | 0.722 | −0.23 (−1.37 to 0.92) | 0.694 |
Employed/self-employed | −0.45 (−4.04 to 3.15) | 0.807 | −0.01 (−2.55 to 2.54) | 0.997 | −0.81 (−2.63 to 1.01) | 0.379 | 0.16 (0.89–1.22 | 0.764 | −0.04 (−1.18 to 1.10) | 0.946 |
Education, yrs | ||||||||||
< 10 | −2.51 (−7.61 to 2.60) | 0.334 | −1.23 (−4.84 to 2.39) | 0.054 | 1.01 (−1.57 to 3.59) | 0.440 | −1.06 (−2.53 to 0.042) | 0.160 | −0.86 (−2.47 to 0.34) | 0.289 |
11–13 | 1.21 (−1.99 to 4.42) | 0.458 | 0.97 (−1.31 to 3.24) | 0.403 | −0.08 (−1.70 to 1.54) | 0.926 | −0 to 42 (−0.98 to 0.90) | 0.930 | 0.34 (−0.68 to 1.36) | 0.511 |
> 13 | Ref. | Ref. | Ref. | Ref. | Ref. | Ref. | Ref. | Ref. | Ref. | Ref. |
Exercise < 1 h/week | −3.79 (−7.93 to 0.35) | 0.072 | −1.93 (−4.86 to 1.00) | 0.196 | 0.05 (−2.02 to 2.14) | 0.961 | −0.54 (−1.75 to 0.07) | 0.377 | −1.17 (−2.48 to 0.14) | 0.080 |
Current smoker | −1 to 33 (−4.63 to 1.97) | 0.427 | −1.48 (−3.81 to 0.87) | 0.218 | 0.11 (−1.57 to 1.78) | 0.901 | −0.05 (−1.01 to 0.92) | 0.924 | 0.12 (−0.93 to 1.17) | 0.821 |
Alcohol, per week | ||||||||||
Never | −0.34 (−6.15 to 5.47) | 0.908 | −1.02 (−5.13 to 3.10) | 0.626 | 1.54 (−1.39 to 4.48) | 0.302 | −0.31 (−2.01 to 1 to 38) | 0.717 | −0.40 (−2.24 to 1.44) | 0.667 |
1–6 glasses | 2.23 (−2.64 to 7.11) | 0.367 | 1.24 (−2.21 to 4.69) | 0.480 | −0.51 (−2.97 to 1.95) | 0.683 | 0.93 (−0.51 to 2.36) | 0.204 | 0.60 (−0.96 to 2.15) | 0.451 |
≥ 7 glasses | Ref. | Ref. | Ref. | Ref. | Ref. | Ref. | Ref. | Ref. | Ref. | Ref. |
BMI (kg/m2) | −0.36 (−0.69 to −0.03) | 0.034 | −0.29 (−0.52 to 0.06) | 0.015 | 0.15 (−0.2 to 0.32) | 0.075 | −0.11 (−0.21 to 0.02) | 0.021 | −0.09 (−0.20 to 0.01) | 0.088 |
Disease activity measures | ||||||||||
BASDAI (range 0–10) | −0.14 (−1.42 to 1.14) | 0.829 | −0.35 (−1.25 to 0.56) | 0.455 | 0.17 (−0.48 to 0.82) | 0.601 | 0.04 (−0.34 to 0.42) | 0.840 | 0.02 (−0.40 to 0.42) | 0.967 |
MASES (range 0–13) | 0.11 (−0.34 to 0.55) | 0.639 | 0.03 (−0.29 to 0.34) | 0.863 | −0.10 (−0.33 to 0.12) | 0.367 | 0.07 (−0.06 to 0.20) | 0.291 | 0.10 (−0.06 to 0.24) | 0.182 |
CRP, mg/dl | −0.15 (−0.29 to −0.02) | 0.026 | −0.9 (−0.19 to 0.003) | 0.059 | 0.04 (−0.03 to 0.11) | 0.224 | −0.05 (−0.09 to −0.01) | 0.015 | −0.05 (−0.19 to −0.01) | 0.017 |
Health status | ||||||||||
BASFI (range 0–10) | 0.14 (−1.41 to 1.69) | 0.857 | 0.52 (−0.57 to 1.62) | 0.348 | −0.56 (−1.34 to 0.23) | 0.162 | 0.07 (−0.38 to 0.53) | 0.748 | 0.02 (−0.47 to 0.52) | 0.924 |
BAS-G (range 0–10) | −1.70 (−2.74 to −0.66) | 0.002 | −1.36 (−2.10 to 0.63) | < 0.001 | 0.65 (0.12–1.18) | 0.016 | −0.49 (−0.80 to 0.19) | 0.002 | −0.42 (−0.75 to 0.09) | 0.013 |
HAQ (range 0–3) | 2.45 (−2.72 to 7.62) | 0.351 | 0.55 (−3.11 to 4.21) | 0.766 | 0.89 (−1.72 to 3.50) | 0.503 | 0.59 (−0.93 to 2.11) | 0.443 | 0.25 (−1.40 to 1.90) | 0.767 |
Damage | ||||||||||
BASMI (range 0–10) | 0.18 (−6.69 to 1.05) | 0.667 | 0.21 (0.41–0.82) | 0.507 | −0.18 (−0.62 to 0.26) | 0.412 | 0.04 (−0.21 to 0.30) | 0.752 | 0.10 (−0.17 to 0.38) | 0.463 |
Comorbidity, mean total score range 0–10 | −1.65 (−3.55 to 0.25) | 0.088 | −0.75 (−2.10 to 0.60) | 0.275 | 0.30 (−0.66 to 1.26) | 0.542 | −0.55 (−1.11 to 0.00) | 0.052 | −0.56 (−1.16 to 0.46) | 0.070 |
Current treatment | ||||||||||
NSAID | −0.002 (−3.03 to 3.03) | 0.999 | −0.37 (−2.52 to 1.77) | 0.733 | 0.31 (−1.23 to 1.83) | 0.695 | 0.23 (−0.66 to 1.12) | 0.616 | −0.01 (−0.97 to 0.96) | 0.986 |
Synthetic DMARD | 2.61 (−4.23 to 9.47) | 0.454 | 1.00 (−2.86 to 6.86) | 0.419 | −1.02 (−4.49 to 2.45) | 0.564 | 0.92 (−1.10 to 2.94) | 0.373 | 0.69 (−1.51 to 2.88) | 0.538 |
Biologic DMARD | 6.43 (2.85–10.01) | < 0.001 | 3.91 (1.38–6.45) | 0.003 | −0.68 (−2.49 to 1.13) | 0.459 | 1.89 (0.84–2.93) | < 0.001 | 1.17 (0.03–2.30) | 0.044 |
Center, SSHF (N/Y) | 1.66 (−1.88 to 5.22) | 0.357 | 2.31 (−0.21 to 4.82) | 0.072 | −2.18 (−3.97 to 0.38) | 0.018 | 0.65 (−0.40 to 1.69) | 0.224 | 0.80 (−0.33 to 1.04) | 0.165 |
R2, % | 16.5 | 16.7 | 9.7 | 16.9 | 16.3 |
Adjusted analyses were performed using multiple regression analyses and applying a general linear model using SPSS Statistics. Adj: adjusted unstandardized regression coefficients with 95% CI and p values. SQOL: sexual quality of life; BMI: body mass index; BASDAI: Bath Ankylosing Spondylitis Disease Activity Index; MASES: Maastricht Ankylosing Spondylitis Enthesitis Score; CRP: C-reactive protein; BASFI: Bath Ankylosing Spondylitis Functional Index; BAS-G: Bath Ankylosing Spondylitis Global Score; BASMI: Bath Ankylosing Spondylitis Metrology Index; HAQ: Health Assessment Questionnaire; NSAID: nonsteroidal antiinflammatory drugs; DMARD: disease-modifying antirheumatic drugs; SSHF: Sorlandet Hospital, Norway.